Cervical Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Treatment Options by Stage

Carcinoma in Situ (Stage 0)

Treatment of carcinoma in situ (stage 0) may include the following:

  • Conization, such as cold-knife conization, loop electrosurgical excision procedure (LEEP), or laser surgery.
  • Hysterectomy for women who cannot or no longer want to have children. This is done only if the tumor cannot be completely removed by conization.
  • Internal radiation therapy for women who cannot have surgery.

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage 0 cervical cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. Talk with your doctor about clinical trials that may be right for you. General information about clinical trials is available from the NCI Web site.

Stage IA Cervical Cancer

Stage IA cervical cancer is separated into stage IA1 and IA2.

Treatment for stage IA1 may include the following:

  • Conization.
  • Total hysterectomy with or without bilateral salpingo-oophorectomy.

Treatment for stage IA2 may include the following:

  • Modified radical hysterectomy and removal of lymph nodes.
  • Radical trachelectomy.
  • Internal radiation therapy for women who cannot have surgery.

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage IA cervical cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. Talk with your doctor about clinical trials that may be right for you. General information about clinical trials is available from the NCI Web site.

Stages IB and IIA Cervical Cancer

Treatment of stage IB and stage IIA cervical cancer may include the following:

  • Radiation therapy with chemotherapy given at the same time.
  • Radical hysterectomy and removal of pelvic lymph nodes with or without radiation therapy to the pelvis, plus chemotherapy.
  • Radical trachelectomy.
  • Chemotherapy followed by surgery.
  • Radiation therapy alone.

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage IB cervical cancer and stage IIA cervical cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. Talk with your doctor about clinical trials that may be right for you. General information about clinical trials is available from the NCI Web site.

Continued

Stages IIB, III, and IVA Cervical Cancer

Treatment of stage IIB, stage III, and stage IVA cervical cancer may include the following:

  • Radiation therapy with chemotherapy given at the same time.
  • Surgery to remove pelvic lymph nodes followed by radiation therapy with or without chemotherapy.
  • Internal radiation therapy.
  • A clinical trial of chemotherapy to shrink the tumor followed by surgery.
  • A clinical trial of chemotherapy and radiation therapy given at the same time, followed by chemotherapy.

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage IIB cervical cancer, stage III cervical cancer and stage IVA cervical cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. Talk with your doctor about clinical trials that may be right for you. General information about clinical trials is available from the NCI Web site.

Stage IVB Cervical Cancer

Treatment of stage IVB cervical cancer may include the following:

  • Radiation therapy as palliative therapy to relieve symptoms caused by the cancer and improve quality of life.
  • Chemotherapy and targeted therapy.
  • Chemotherapy as palliative therapy to relieve symptoms caused by the cancer and improve quality of life.
  • Clinical trials of new anticancer drugs or drug combinations.

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage IVB cervical cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. Talk with your doctor about clinical trials that may be right for you. General information about clinical trials is available from the NCI Web site.

WebMD Public Information from the National Cancer Institute
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.Some material in CancerNet™ is from copyrighted publications of the respective copyright claimants. Users of CancerNet™ are referred to the publication data appearing in the bibliographic citations, as well as to the copyright notices appearing in the original publication, all of which are hereby incorporated by reference.

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