Colorectal Cancer: 9 Things That Raise Your Risk

Anyone can get colorectal cancer, and doctors often don't know why someone gets it.

Although scientists don’t know the exact cause, they do know some of the things that make people more likely to get it. These include:

Age. The disease is most common in people over age 50, and the chance of getting colorectal cancer increases with each decade. But younger people can get it, too.

Gender. Colorectal cancer is more common among men. Men and women are equally at risk for colon cancer, but men are more likely to develop rectal cancer.

Polyps. These growths on the inner wall of the colon or rectum aren’t cancer, but they can be precancerous. They’re fairly common in people over age 50. One type of polyp, called an adenoma, makes colorectal cancer more likely. Adenomas are the first step toward colon and rectal cancer.

Personal history. If you’ve already had colorectal cancer, you could get it again, especially if you had it for the first time before age 60. Also, people who have chronic inflammatory conditions of the colon, such as ulcerative colitis or Crohn's disease, are more likely to develop colorectal cancer than other people.

Family history. Do you have a parent, brother, sister, or child who has had colorectal cancer? That makes you more likely to get it, too. If that relative was diagnosed when he or she was younger than 45 years old, your risk is even higher. If conditions such as familial adenomatous polyposis, MYH-associated polyposis, or hereditary non-polyposis colorectal cancer run in your family, that raises the risk for colon cancer (and other cancers), too.

Diet. People who eat a lot of fat and cholesterol and little fiber may be more likely to develop colorectal cancer.

Lifestyle. You may be more likely to get colorectal cancer if you drink a lot of alcohol, smoke, don't get enough exercise, and if you are overweight.

Diabetes. People with diabetes are more likely to develop colorectal cancer than other people.

Race. African-Americans are more likely than other U.S. racial and ethnic groups to get colorectal cancer. Doctors don’t know why that is.

If you have one or more of these risk factors, it doesn’t mean that you will develop colorectal cancer. But you should talk about your risk factors with your doctor. She may be able to suggest ways to lower your chances and tell you when you need to get checked.

WebMD Medical Reference Reviewed by Louise Chang, MD on August 04, 2018



National Cancer Institute: "Colorectal Cancer Screening (PDQ)" and "What You Need to Know About Cancer of the Colon and Rectum."

American Cancer Society: "Colorectal Cancer Overview."


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