THIOTEPA Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • an unusual viral infection called cytomegalovirus infection
  • an infection
  • anemia
  • decreased blood platelets
  • low levels of white blood cells
  • low levels of a type of white blood cell called neutrophils
  • bleeding
  • stomatitis, a condition with painful swelling and sores inside the mouth
  • high amount of bilirubin in the blood
  • abnormal liver function tests

If experienced, these tend to have a Less Severe expression i

  • bloody urine
  • diarrhea

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • a reduction in the body's resistance to infection
  • bleeding within the skull
  • high amount of uric acid in the blood
  • reactions at the site of the injection

If experienced, these tend to have a Less Severe expression i

  • blurred vision
  • pink eye
  • low sperm count
  • absence of menstrual periods
  • irregular periods
  • skin inflammation
  • itching
  • hair loss
  • skin discoloration
  • dizziness
  • fever
  • low energy
  • decreased appetite
  • headache
  • nausea
  • an inability to completely empty the bladder
  • generalized weakness
  • intense abdominal pain

RARE side effects

If experienced, these tend to have a Severe expression i

  • leukemia
  • suicidal thoughts
  • a type of brain function problem called encephalopathy
  • vision loss
  • pulmonary hypertension
  • inflammation of the covering of the heart or pericardium
  • fluid in the covering of the heart or pericardium
  • slow heartbeat
  • chronic heart failure
  • subdural intracranial hemorrhage
  • a stroke
  • hepatic veno-occlusive disease, a type of liver disease
  • vocal cord swelling
  • inflammation of the small and large intestine
  • kidney failure
  • inflammation of the bladder
  • inflammation of the bladder with hemorrhage
  • a skin disorder with blistering and peeling skin called toxic epidermal necrolysis
  • a skin disorder with blistering and peeling skin called Stevens-Johnson syndrome
  • blistering of the skin
  • coma
  • seizures
  • wheezing
  • trouble breathing
  • an enlarged liver
  • ascites
  • a significant type of allergic reaction called anaphylaxis
  • disorder of lymphoid tissue after transplant
  • malignant lymphoma
  • multiple organ failure

If experienced, these tend to have a Less Severe expression i

  • confusion
  • depression
  • behavioral problems
  • drooping of the upper eyelid
  • asthma
  • a type of stomach irritation called gastritis
  • abnormal peeling of skin
  • drowsiness
  • delirium
  • memory loss
  • abnormal manner of walking
  • difficulty swallowing
  • a feeling of general discomfort called malaise
  • indifferent behavior
  • slowness of movement
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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.