What should I Know Regarding Pregnancy, Nursing and Administering PACLITAXEL to Children or the Elderly?
If you are PREGNANT
- Not Recommended:
If you are NURSING
- Precaution: NOT RECOMMENDED, POTENTIAL FOR SEVERE ADVERSE EFFECTS IN INFANT
If you are an adult over 60
- management or monitoring precaution: General-Increased risk of grade IV neutropenia and myelosuppression. Cardiovascular-Increased incidence of CV events (bradycardia, hypotension, abnormal ECG) and pulmonary edema. Neuro/Psych-Elderly experienced an increased incidence of peripheral neuropathy. Hepatic-Adjust dose as recommended for hepatic impairment. Gastrointestinal- Increased incidence of diarrhea, decreased appetite, dehydration in elderly.
Giving Haloperidol to a child under 12
- Severe Precaution: Rare reports of CNS toxicity. No safety and efficacy established in pediatrics.
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