User Reviews for Lupron Depot intramuscular

I have endo, fibroids, and ovarian cysts. First time I took it (monthly injection for 6 months), was symptom free for five years. Hoping for great results again this time (3-month dose taken twice). Get some hot flashes and night sweats but a small price to pay for the pain relief.

I'm 35 years old and suffered from chronic pain on my right side that would radiate to my back. After about 5 pelvic ultra sounds I had one bad episode that sent me to the ER where they found that I had a cyst the size of a grapefruit on one of my ovaries. I had surgery to have it removed and once the doctor opened me up he said it was a mess inside. My inside was filled with a bunch of blood. Once I had the ovary and all the blood removed I started to feel pain on the other ovary, but within a month I started Lupron and my life changed! Since I've been on it I haven't had any pain. The down side to it is that I do get the night sweats, and hot flashes. The worst side effect is the loss of sex drive. I went from having a very active sex life to not wanting to have sex at all. Luckily, my boyfriend has been very understanding. I just got my second (last) shot last week and I'm nervous that the pain will come back. I'm confident my new doctor is doing all he can to treat me because I couldn't imagine where I'd be if I was still seeing my same OBGYN. Read More Read Less

I have been dealing with increasing pain and bleeding during menstrual cycles for the last 6 years. I thought that it was a normal process of getting older (my mother had similar issues). After developing a mass in my groin I decided to seek advice from a doctor. They told me that I had a hernia and that it was not a concern for treatment at this time. I sought advice again when I started bleeding from my bowels on a monthly basis with excruciating pain. It has taken over three years (from the first time I sought advice) to finally get a diagnosis of Endometriosis. Even as I went in for surgery, my surgeon was not convinced that I had endometriosis and he thought I had a hernia causing all of my symptoms. After surgery, they said that I was in advanced stages of Endometriosis. I have already started Lupron (1st shot in July) and it has been a blessing. Yes that hot flashes, night sweats, uncontrollable emotions, and irritability are overwhelming; but I not have a control over the pain and bleeding. The best advice I have is to listen to your body. You know it better than anyone else and if you are concerned about something then seek advice and don't give up until you are comfortable with the diagnosis. It may take 6+ years and 20+ different doctors; but your health is worth it.Read More Read Less

The side effects are horrible, but hopefully it was all worth it!! The hot flashes/night sweats are constant, and I'm very grouchy. Nothing fun about this drug what so ever. We shall see soon how well it worked.

Since end of last yr/early of this yr, my periods became extremely heavy flow during the first 3/4 days...went to see Dr. she ordered an ultrasound, found out I have 2 fibroids...one is about 5cm & the other about 4cm. While waiting to see gyno, my family dr. gave me a prescription "Cyklokapron" to help with the bleeding. But it actually made it worst for me...the bleeding was non stop for months. I went into emergency twice - both Dr. told me that the prescription is not strong enough so I need to increase the dose. I didn't increased it as I was getting other side effects from this drug. My pain was getting more intense & hemoglobin was very low so my family Dr. told me to go to hospital to get blood transfusion. Had to request an emergency to see the Gyno...finally got in to see her, she too told me that I need to double my dose. So I listened to her but it got worse! She told me to take Lupron to help stop the bleeding & reduce the size of fibroids before the surgery. The first 2 wks of the injection of Lupron, the side effects were mild but by the 3rd wk, I woke up to a terrible headache, dizzy & nauseous. The hot flushes got more frequent & intense too. The bleeding only stop during the 4th wk of my first injection. I'm now on the second injection, however, the side effects like everyone here mentioned are the same-terrible! Hot flushes, rapid heart beat, sometimes I feel shortness of breath, fatigue and I also noticed that my breasts has also shrink as it mentioned "breast changes", on & off cramps, back aches, etc. Told the Gyno about my symptoms, she said it's related to my anemic as my hemoglobin was at 82. My gyno. said I need to top up my hemoglobin before the surgery (the earliest scheduled is in Oct.). So I tried the i.v iron injection but had allergic reaction so now I'm taking Feramax iron pills twice a day and calcium 2x a day. I do not want to take the next injection as the side effects are terrible & it's seriously wearing me down!Read More Read Less

My endo symptoms really got bad after my daughter was born (C-Section). Very heavy blood flow for days, to the point where I was changing super plus tampons every 45 minutes and clots larger than golf balls. The pain? Excruciating! Ive wanted a hysterectomy for years but every doctor I saw told me they wouldnt do it because I was too young. (I was 20 when my daughter was born) The OBGYN I see now, prescribed Lupron for me every 3 months for 1 year. I just had my 3rd shot in April....NO PAIN AT ALL. Its wonderful. Yes, there are side effects, hot flashes are really annoying, sweating all the time, and zero libido. To me, these side effects are completely worth it. I no longer have to feel like my bladder and other organs are 'bouncing' with each step I take. The fact that I have a very compassionate husband helps too. Read More Read Less

My OB-GYN recommended this treatment for diagnosing whether I had endometriosis. He told me that it would help if I did or it would make my symptoms worse if i didn't. I had very few side effects, and it helped immensely! I had the treatments for 6 months. My last shot was in February and I haven't had any problems since. The only thing is that it has been almost 4 months since my last shot, and I still haven't had my period. I don't really mind except me and my husband are trying to get pregnant. At least we are getting plenty of practice in ;)Read More Read Less

I had this injection 3 monthes ago , i was scared by reading some of the rievews. however after i took the shot, i was really satisfied with the result, the only sideeffect i experinced was hot flashes, no joint pain or gaining weight.

I have taken two shots so far. After the first shot I begin to have hot flashes, night sweats and upset stomach. I did still have severe cramps still but no bleeding . By the second shot I had all the above symptoms along with severe joint pain to the point of going to a physical medicine doctor and having to get a MRI that stated that I had a meniscus tear in my knee and arthritis which has caused me to be off work for almost two weeks already. I was referred to an orthopedic surgeon and may possibly need surgery. I believe the medication cause weakness in my joints making it easier for injury. I have already paid for the third shot and it has been delivered to the doctor but I am going to refuse to take it. I will just move forward with getting the ablation surgery after my knee issues are taken care of. I'm also experiencing anxiety really bad along with not being able to sleep. So no telling what the third shot might bring on. So for me even though it helped the side effects were worst then the benefits. Read More Read Less

I have pretty severe endometriosis to the point where the endo was into my bladder and causing me to have to go to the bathroom 11+ times a day, sometimes not making it. I'm only 32 so this was totally unacceptable. Started out as bladder infections about 5 years ago, turned into bladder pain, birth control kind of helped but my blood pressure would go through the roof and on my period weeks I would suffer. The endo causing the issue was 3 inches, after 5 months its now 3 cm!!! Noticeable difference. I go in to remove the rest of it tomorrow. This saved me from months on a catheter!!!! I only had two noticeable hot flashes. I'm not going to candy coat it, I was in the hospital the first month for what I thought was a stomach virus. Second month I had something similar but it was only one month later to the day. You may want to ask your doctor about anti nausea meds for just the first two months and seriously, its only a just in case. I've had 5 years with this endo/bladder issue and I'm finally going to be getting rid of it. Lupron definitely helps. I did get the add back but I would only use it when I noticed memory issues, aches, or flashing. I don't know if it was how I took it but I had one shot per month. Maybe the monthly dosage was easier on my body. Reading reviews like this scared me into not taking it for the first few years, now I'm mad at myself for not doing it earlier. My hair was even starting to drop out because the endo was messing up my hormone levels. Also, highly recommend taking this during the winter. My body temp always felt warmer.Read More Read Less

When started PSA 7.0. Treatment Lower my PSA to 0.3 in the first year of use. My sex drive went to zero and hot flashes most days. Have joint pain and lower back pain in a.m. When first get out of bed, but usually goes away after out of bed for a few hours.

My GyneOB recommended I take these shots for 6 months following my surgery to remove a HUGE fibroid as well as a cyst on each ovary. During surgery, she discovered that I also had a severe case of endometriosis. She said that the Lupron Depot would help get rid of the endometriosis. Each month I took a shot in a hip (alternating each month). I researched all the possible side effects but still was not prepared for them! The ones that chose me were the lovely hot flashes, night sweats, joint pain, decreased(basically extinct) libido and vaginal dryness. My Dr. suggested that I only take 6 treatments, then take a break, which I did but the side effects lasted at least another 4-6 months! I can't see where the shots even helped! I had to have a laproscopic surgery last year for another cyst removal and the endometriosis was worse than before! I had so much scar tissue that I now have one completely block fallopian tube and one partially blocked. So now, my husband and I are on mission impossible trying to get pregnant (for more than a year now). I also have horrible joint pain still especially in my hips where the treatments were administered. Be very careful, Ladies. I do not recommend this drug. If you absolutely have to take something to treat your issue (like I did), do your research...but also mentally prepare yourself for the life-altering side effects! Or maybe you'll be blessed like some of the other reviewers and have minimal or no side effects at all. :-) Good luck and be blessed.Read More Read Less

Run!!!! Do not take this drug. It will ruin your life. Still having side effects a year later and it made my problem 100000x worse. It should never be given to a patient. DO NOT TAKE.

I LOVE Lupron. I have had endo for 4+ years and 2 of which went undetected and with horrible pain. I have been on Lupron for 18 months and about to start my next 6 month session. I do experience some of the "menopause symptoms" but I'll take it compared to the horrible pains that I had with Endo. I've had two bone scans to ensure my bones haven't been weakening and so far do good! Since its only recommended to be on it no more than 2 years, I'm entering my last 6 months and this saddens me... I love how convenient it is and most importantly how well it works! Read More Read Less

I had the worst experience with this Drug. Every side effect plus I broke-out on my back and it didn't work. I ended up having a myomectomy anyways. It was a total waste of time and Abbott Endocrinology screwed up the billing on several occassions.

Prescribed series of 3 shots for treatment of endometriosis and uterine fibroids before scheduled hystorectomy. Stopped menstrual cycle and cramps which was great. However, severely compromised my mental stability. After second shot I developed extreme anxiety/panic attacks, unable to eat or sleep, hot flashes/flushes, electric shock/fluttering feeling in my heart and acne. Declined 3rd shot and still trying to get myself back in balance before my surgery. Research to make the best informed decision!!!!!!!! Read More Read Less

Since being on the injections I have been diagnosed with Obstructive Sleep Deprivation and Memory problems, depression and weight gain.

The first time I I went on Lupron , I had stage 5 , the first 4 to 6 months were ruff , lots of hot flashes night sweats , dry mouth, but as time went by it got better , the pain got so much better, I went from pain on a scale of 1-10 usually a 8 to 0 after about 9 months , yes there is lot of uncomfortablity, to this shot , I went off after 1 year , symptoms free , but 2yrs later the emdometrosis is back , I started the shot gained a month ago , going to have my 2shot tomarrow , you have to weight the pros and the cons, it's not right for everyone , I don't want to take it but I also don't want a hysterectomy, there is no real cure for this disease , I've been living with it for 30 something yrs, it's been just getting worse as I age, good luck to all woman , who need too take it ,I font want to but I need relief , that melds don't give you.Read More Read Less

I had Lupron Depot 3 Month 11.25 mg. I was told that the first two weeks were supposed to be horrible, but for my surprise I felt better. On the third week some of the bad symptoms started, hot flashes, headaches, cramps that don't go away, joint pain, I feel weak. I don't have any depression, mood changes, and or night sweeting. I have notice a reduction on my stomach which means my fibroids might have gotten smaller. I would recommend this medication if you are having surgery afterwards, but be prepare for the pain. I don't know how satisfied I am yet since this is my third week and the medication is supposed to last 3 months. I will come back and write about my experience in 3 more months.Read More Read Less

I have received one of these shots to try and assist with my endo and uterine fibroids. The doc that issued this drug to me did not inform me of any of the horrible side effects it causes. I am 24 years old and feel like I'm going through Menopause! Electric tingly sensations, hot flashes, night sweats, headaches, mood swings, dizziness, nausea... need I go on? This drug has made me worse off than I was previously. Unless surgery for you is completely not an option I WOULDN'T get this shot. It sucks.Read More Read Less