User Reviews for Qulipta oral

I've been taking Qulipta for two days. I have had no headaches, which is awesome but a little early to tell for certain. My issue is that for the past two days, I have sleep for 13 hours. I cannot deal with that. I suffer from chronic fatigue anyway and had just had amazing results with Rexulti. I can't sacrifice those results. I'd like to get off narcotics., but not at the sacrifice of sleeping half the day. I am writing in the hope someone has similar side effects and can tell me to take it in the morning and it will help or tell me I'll adjust. I need a little encouragement. I can take it if someone who has taken it longer will let me know this is temporary or how they helped this issue. Thanks! Read More Read Less

I have had migraines since I was 12 years old and I am now 63. I started on Cafergot and used everything since then, including induced sleep to try and have it go away. Imitrix was used for years, with great relief, but no stopping of headaches. I used it almost daily and my kidneys are nearly ruined, I am in stage 3 of kidney disease. I now use Kepra, Botox, Amovig injection with a huge difference but still had headaches a few times a week. I was given samples of Quilipta and I can only describe my results as a miracle no headaches in 8 days. I have had no side effects. Read More Read Less

Started QULIPTA 60 mg daily Jan 1st after being on Emugality, first week I had no migraines , feeling very excited but very fatigued, slightly dizzy , and nauseated, waiting it out now on 4 th week have had breakthrough migraines several days a week, but I was also sick early Jan , tested neg for covid but suspect it was covid I had , it may have affected my migraines , still feeling fatigue ... very tired , hoping this wears off as some have stated it did for them , also have dropped some weight as I'm not too hungry most of the time and eat small portions , that's a plus with the pandemic weight gain , I'm going to give it some more time before I switch back to emugality, that had been thus far after taking every under the sun the only thing that worked , time will tell .... no other issues with the pill except those mentioned here , hoping these side effects will lessen ....Read More Read Less

This med makes me so tired I fall asleep on the couch at 6 pm.

Pros- Practically headache and migraine- free for almost 2 months. They are easier to treat when’ I get the occasional headache, where as before they would last for days on end, even with my rescue medication. Cons- somewhat minor given the benefits, but I am extremely cold in my feet and hands, especially at night. I wear thick socks after work and bought a heated blanket to cope with it but it only provides temporary relief. It is worth looking into CGRP and Reynauds Phenomenon if you can relate to these side effects. Also was constipated for the first 6 weeks but daily miralax helped tremendously and this is no longer an issue. Unintentional weight loss, but this seems to have evened out. I sort of feel indifferent to food and feel fuller, faster. Taking Qulipta at night helped with the brain fogginess. All things considered, this is my miracle drug. I can now be the best mom/wife/teacher I can be! Read More Read Less

For eight days I’ve been on Qulipta as I transitioned off Emgality (had breakthrough migraines on the latter). Today would have been my next Emgality treatment and I’m having a massive migraine with severe nausea. Had to take a sumatriptan booster. Sure hoping as some of you said that it eases.

For the past 4 years I have headaches almost every single day, in varying degrees. I have now been taking Qulipta 60mg daily for a little over three weeks. Since day 1, I have had ZERO headaches. I am kind of in shock about it and knocking on wood as I write this. It is a MIRACLE. The only negative would be that it does cause slight constipation, but I added in Magnesium supplements and they are helping. Also, I will gladly deal with that over the headaches.... I never write reviews, but if this review could help one other person suffering in the way I have been.... I hope everyone has the same experience that I have and finds some relief. Living with headaches is such a struggle.Read More Read Less

With chronic migraine I've tried most everything. From Botox to emgality. With Qulipta I've been super nauseous! Still having migraines. It's been one week. Did the nausea get better for you guys? Debating whether or not to continue taking at this point

I’ve been a migraine sufferer for 28 years. I’ve tried everything from birth control pills, injectables, daily medications, relax, Botox, occipital nerve blocks and nothing has worked like qulipta! I’ve been on it now for 2 1/2 months and it’s amazing. I was dizzy in the beginning but that seems to have lessened. Thank you!

Finished my first month of daily use. Had ZERO migraines. I couldn’t believe it and pray it continues. A month with no migraine is foreign to me. Hope it continues - I’ll give an update after a full 3 months.

I have tried all kinds of treatments for migraines- the worst was Botox- sunken temples- neck and shoulder weakness - did not help migraines- Qulipta is amazing ! I had migraines every time the weather changed lasting sometimes for 4 days. Was nauseated for a few weeks- take it after supper and it helps - seemed to help with the temporary fatigue too. It was all worth it by not having a migraine. Just have had a slight headache a couple of times. Almost on my 3rd month now .

I've been on Qulipta for 5 weeks now and was initially wowed as it really worked. I am almost never without some level of headache (migraine sufferer for nearly 30 years) and I had none or just mild twinges while on it, but now I just don't think I can put up with the side effects any longer. Extreme fatigue, constipation, loss of appetite, heart palpitations and reflux. Cutting the dose and a bit more time on it helped some with fatigue and the loss of appetite but other symptoms persist and the heart issue has worsened. Be aware, though, there are 3 doses 10mg, 30mg and 60mg. If you read the studies there is only a slight reduction in effectiveness between the max and min dose, so do try a lower dose if you have side effects as that might help. My Dr. just told me to stop--so now I'm going back to just Ubrelvy for abortive treatment which thankfully gives me no side effects but does take 4 hours to work.Read More Read Less

I started Qulipta the week of Thanksgiving at 60 MG every day. Since taking it, I have only experienced one migraine and one small-ish headache. Typically I would experience at least 1-2 migraines a week that would last roughly 1-3 days. For me, Qulipta has been a game-changer in that my migraine days have been reduced and the severity of them has also been reduced as well. When I experienced what I would consider a "migraine", I took two (2) extra strength Tylenol which surprisingly took the migraine away. This would never have been the case pre-Qulipta. Other medications I've tried in the past include Ubrelvy, Emgality, Nurtec, Topamax, several types of triptans, Excedrin, Tylenol, CBD oil as well as THC, Lexparo, and Lamotrigine. The only issue I had with Qulipta was waiting the three weeks to finally get the prescription squared away with their pharmacy. That was a massive headache! I would definitely recommend this medication to others with chronic migraines and I hope it works as well for you as it has for me!Read More Read Less

I've been taking Qulipta for about a month. I initially had a few migraines that were controlled with with Rizatriptan but I must say that I have noticed over the last 3 weeks that I have had no migraines. There were a few times that I thought one might be starting but no migraine started. I've had no side effects. No nausea, brain fog, irritability or constipation. I have however lost about 15 pounds since starting the medication (and yes I could stand to lose this 15 and bout 20 more to go along with it) with little to no effort. I have tried aimovig, which was ineffective and gave me severe constipation, emgality which was slightly effective, Topimax, which gave me brain fog and had me so disoriented that I could not drive, Nurtec which did not stop my migraines, Ubrelvy which made my sleepy but did not work and most triptans to stop an existing migrains. Rizatriptan usually works to end an active migraine if I'm taking a preventative medication as well. Hope this helps someone!Read More Read Less

I have suffered chronic migraines for years and tried several different preventative medications. I’ve been on Qulipta for 3 weeks, along with magnesium, and have only have one mild migraine the entire time which responded to excedrin. This medication seems to be a game changer for me with no real side effects but like other reviewers said I’m afraid to jinx it!

I have experience a chronic, persistent headache for the past 4 years. Every second of every day I feel it. I even remember the morning it started (March 15th, 2018). I had never gotten a migraine or tension type headache, so it was a shock for me (a 23 year old in good shape w/ no other health conditions). I have been involved with my healthcare providers since. I work at a State hospital, so the onsite care is above average. That said, I made a trip to the Mayo Clinic just to make sure I wasn't about to drop dead. They re-iterated my neurologist back home, except for the description. While my neuro felt I had an unremittent migraine, Mayo believed it was a 24/7 tension type headache with myofascial pain. Mayo's description was more accurate, but it is important to remember that head pain has overlapping pathways no matter the diagnosis. Over the past four years I've had multiple scans of my head, sinuses, and back. I've seen an ENT, allergist, and cardiologist in addition to multiple neurologists. None were able to provide a rationale for my pain. I've tried every OTC under the sun. I've taken consistent baths, used heating pads, and tried massage. At best these things lightened the pain, which always fully returned. I've tried the following: Gabapentin, Lamotrigine, Topamax, Carbamazepine, Melatonin, Aimovig, Adderall, and Ritalin. Of these, Topamax was decent (although the side effects were less than ideal) and stimulants helped with the pain (slightly) and brain fog. Lamotrigine lessened the number of bad days, but didn't decrease the pain on the bad days (Topamax did). Last night was my first dose of Qulipta. I took it when the pain was extremely bad. I immediately felt relief. Today, I feel amazing. It is the best, most immediate response I have had to any medication. This is a bit of a shock, as Aimovig (which targets the same receptor) was ineffective. Hopefully Qulipta, alongside lamotrigine, continues to work. Some other reviews mention a decrease in effectiveness, so I'll give an update in a few weeks. A good take away is that head pain, migraine or not, shares similar signaling pathways. DON'T convince yourself that non-migraine head pain won't respond to migraine treatment. All the best.Read More Read Less

Only one week in. Still getting headaches, one right now. Side effects so far: -Bad constipation -Nausea a few nights -Fatigue, I've been fighting fatigue post-covid but it has worsened since I started qulipta -Insomnia, uncertain if related Starting to wonder if it is worth it, especially with the insurance hassle.

I’ve been taking Qulipta for 2 weeks. I have chronic migraines. I haven’t had a migraine since the day I started taking it! No side effects.

I started this during a bout with Covid. I stopped it after a few days because my Covid headache had not improved but after I started feeling better, I resumed it. I have lots of migraine triggers and still avoid them but I am noticing a 90% improvement on this medication so I will continue it. I’ve had to use one imitrex in 3 weeks to get rid of a migraine and that’s a lot of improvement for me. Happy so far. Age 55, migraines for over 30 years.

I've been taking this medicine for 3 weeks now. The first week was great - I had no migraines or headaches at all so I was super optimistic. Unfortunately, the 2nd and 3rd week, I've had lots of migraines, pretty much every other day. On the plus side, my appetite has decreased greatly. I've lost 11 pounds in three weeks. I eat what I normally do, I just feel full after a few minutes of eating.