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3.3 Overall Rating

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Most voted positive review

101 People found this comment helpful

This is honestly the worst drug anyone could ever take. I took 60mg of Duloxetine for over 5 years and had to come off it for surgery. I was initially prescribed it by a psychiatrist and left on it for so long because my GPs didn’t know what it was or what it did. Admittedly, it did the job and helped a lot with my depression and anxiety, but it wasn’t worth it for the withdrawal symptoms I suff...

Shared reviews and ratings

Sacha | 45-54 | Female | On medication for 6 months to less than 1 year | Patient
8/3/2022
Condition: Other
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

I suffer from bipolar disorder II, adhd, and fibromyalgia. I take 15 grains, not grams, but individual grains in the morning and 15 grains at night, 12 hours apart. I also take Vimergy MTHR which is a folate and a b12. I also take lemon balm and cat's claw. The duloxetine at this level has helped me so much with the depression. I take such a small amount due to the fact that my provider wanted me to make sure it wouldn't flip me into mania. It doesn't and it has taken me out of one of the worst depressions I have ever had last fall and I continue to not have depression. I have to take it 12 hours apart because it will start to wear off so I have to be sure to take it. It takes away my body pain and depression. Doctors always raise and eyebrow when they find out that I am taking such a small amount but for me it works, and I need to take it. Everyone is different. Read More Read Less

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Hd2334 | 35-44 | Female | On medication for 1 to less than 2 years | Patient
8/2/2022
Condition: Neuropathic Pain
Overall rating 1.0
Effectiveness
Ease of Use
Satisfaction

Medication is impossible to stop. Interacts with so many medications. Pretty sure it has made my hypertension worse. Doctors should really warn people of how hard this medication is to stop. You literally feel the brain zaps when you are tapering down. It’s just horrible.

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Aaron | Male | On medication for 2 to less than 5 years | Patient
7/23/2022
Condition: Neuropathic Pain
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

Broke my back a couple years ago, have had a spinal fusion resulting in extreme nerve pain and nerve damage in my right leg. It was unbearable. Been taking 120mg for almost 2 years. Haven’t had any noticeable side effects. I definitely wouldn’t be able to survive with out it.

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Adam | 25-34 | Male | On medication for 10 years or more | Patient
7/17/2022
Condition: Major Depressive Disorder
Overall rating 1.7
Effectiveness
Ease of Use
Satisfaction

This drug after 6+ years of taking sertraline hasn't done anything but made me more paranoid and very emotional. Also am dealing with a bout of PTSD and sleep problems. I have a hard time finding a way to take care of my problems without risking my life.

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Peg | 55-64 | Female | On medication for 1 to 6 months | Patient
7/10/2022
Condition: Neuropathic Pain
Overall rating 1.7
Effectiveness
Ease of Use
Satisfaction

Duloxetine is by far the worst medicine I’ve taken. First I experienced major hair loss and then I broke out with hives and welts all over by body and had severe itching. Never take it again.

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XiuXiu | 35-44 | Male | On medication for 5 to less than 10 years | Patient
6/24/2022
Condition: Neuropathic Pain
Overall rating 3.7
Effectiveness
Ease of Use
Satisfaction

Prescribed for depression/anxiety/neuropathic pain about 5 years ago. On 60mg then up to 120mg, then down again. Did it work? Yes despite sexual side effects and excessive sweating, worked great. Even made neuropathic pain stop. Is it hard to come off? Yes - forgot to bring it while traveling a few years ago, and felt like I was going to die: brain zaps, impulsive behavior, emotional swings, weird uncontrollable bodily sensations. Currently, I am slowly reducing dose from 20 mg to zero, and even that feels tough. Doctors really should be obliged to warn patients about withdrawal symptoms before prescribing.Read More Read Less

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Nicole pizzi | 45-54 | Female | On medication for 6 months to less than 1 year | Patient
6/24/2022
Condition: Major Depressive Disorder
Overall rating 1.7
Effectiveness
Ease of Use
Satisfaction

Gave me suicidal thoughts, increased depression

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Nickole | 45-54 | Female | On medication for 1 to less than 2 years | Patient
6/21/2022
Condition: Neuropathic Pain
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

This med has transformed my life, with benefits greater than anything else prescribed to me in terms of reducing pain and improving how I feel. Most especially, my level of alertness. A wonder drug. I have never felt better.

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Erin | 35-44 | Female | On medication for 2 to less than 5 years | Patient
6/7/2022
Condition: Chronic Muscle or Bone Pain
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

This medicine has literally changed my life. Major reduction in my fibro pain. Significant reduction in anxiety and nervousness. Huge change in my quality of life.

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Mcg766 | 55-64 | Male | On medication for 1 to 6 months | Patient
5/30/2022
Condition: Chronic Muscle or Bone Pain
Overall rating 2.3
Effectiveness
Ease of Use
Satisfaction

It was given to because I mentioned suicide if my back pain was not fixed. It leveled out my moods BUT it killed my appetite. I went from 230-170 in a few months. I completely lost the urge to eat at all. My sex drive also took a huge dive.i didn't even think about sex. I stopped the medication and my sex drive also wanting to eat again returned.

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Cathy | 55-64 | Female | On medication for less than 1 month | Patient
5/17/2022
Condition: Neuropathic Pain
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

Have tried everything to help with nerve pain, joint pain, fatigue, depression and anxiety related to CFS/ME and Long Covid. Cymbalta gave me the best relief within a week of using. I can finally go back to my job and my life.

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blackbeartooth | 19-24 | Female | On medication for less than 1 month | Patient
5/2/2022
Condition: Repeated Episodes of Anxiety
Overall rating 1.0
Effectiveness
Ease of Use
Satisfaction

I used to take escitalopram and pregabalin but cannot take them anymore because they interact with my ivabradine heart medication. My psychiatrist prescribed duloxetine for depression and PTSD. It was absolutely horrible. The first time I took it I threw up. Then the next day I was nauseous all day, could not eat, I was fatigued and after about 15 hours since taking it, I started to feel drugged up, I was confused, could not speak or think. I only took it for 3 days, it was horrendous and my body could not tolerate it. Quit cold turkey, 3 days later I am very agitated and angry all the time. Started taking 20mg Paroxetine, hopefully that will be fine, the side effects are minuscule so far compared to how bad duloxetine was. Read More Read Less

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Dan | 45-54 | Male | On medication for 2 to less than 5 years | Patient
5/1/2022
Condition: Major Depressive Disorder
Overall rating 3.3
Effectiveness
Ease of Use
Satisfaction

I have been on this drug for 3 years on the max dose of 120 for depression, EUPD, PTSD, schizotypal personality disorder, I'm currently on about 36 pills a day and still feel suicidal

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JH | 45-54 | Female | On medication for 6 months to less than 1 year | Patient
4/19/2022
Condition: Neuropathic Pain
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

This medicine has greatly reduced my head and neck pain. This had progressed to a chronic daily headache at the base of my skull.

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Anonymous | 45-54 | Female | On medication for less than 1 month | Patient
4/8/2022
Condition: Neuropathic Pain
Overall rating 1.0
Effectiveness
Ease of Use
Satisfaction

I took one pill and within an hour I could Barely move. Frightening experience I called pharmacist and doctor and was told It takes two weeks to get in my system. I don’t care what they said i felt it could kill me.

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Rachel | 19-24 | Female | On medication for less than 1 month | Patient
3/26/2022
Condition: Neuropathic Pain
Overall rating 2.0
Effectiveness
Ease of Use
Satisfaction

I literally took these for 3 days 60mg a day I could not lift my head I was so week my kidneys really hurt the brain fog was horrendous and my scalp started to get blistering sores hp advised it wasn't from these medication but there the only new meds I had been giving for depression 3 days of them and I feel brand new and had to be giving anti bionics for my scalp

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Rhys | 13-18 | Transgender | On medication for 2 to less than 5 years | Patient
3/20/2022
Condition: Major Depressive Disorder
Overall rating 4.7
Effectiveness
Ease of Use
Satisfaction

I've been on at least 10 different meds, this one has made life so much easier for me and I no longer suffer from Depression. It hasn't changed my libido/orgasm at all thankfully like some other drugs have before! It also helps with my migraines which run in my family and make them much less frequent. However I give this a Good Satisfaction Rating because missing a few days (starts at 2-3 days) I experience Brain Zaps and they are very debilitating so I know withdrawing would be hard.

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Ian.Baldwin | 25-34 | Male | On medication for 2 to less than 5 years | Patient
3/14/2022
Condition: Anxiousness associated with Depression
Overall rating 4.0
Effectiveness
Ease of Use
Satisfaction

I started taking this medication due to experiencing severe depression panic attacks and generally unstable mood. To that end, the medication is effective. Even to the point where I do not cry under circumstances it probably should happen. My experiences with side effects have been drowsiness, increased metabolism, absolutely no sex drive, and dehydration. If I forget to take a dose (which does not happen often) I cannot concentrate, am extremely short-tempered and when I finally take the next dose I often have diarrhea. Read More Read Less

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Sad | 75 or over | Female | On medication for less than 1 month | Patient
3/9/2022
Condition: Chronic Muscle or Bone Pain
Overall rating 2.0
Effectiveness
Ease of Use
Satisfaction

Took one pill and within half hour the diarrhea started, migraine, muscle pain. I got ulcers all over my tongue by midafternoon. The diarrhea did not stop and got so bad; it threw me into dehydration. I was like this for three days. Could not think straight, blurred vision, chills. For me this drug was a horrible experience. The pill was tan so I figured I could take it, but I am allergic to blue dye. There is blue dye #1 in the pill and blue dye #1 in the coating. I always have to ck the pills for color allergic to blue dye in medicine. I had the pharmacist ck the pill for color and it was tan so we thought I could take it. WRONG!!! It has taken me over 6 days to get it out of my system. NEVER again. I have bad pain from knee surgery from almost a year ago and that is why pain mgt suggested it. Glad it works for other but certainly not for me. Read More Read Less

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Rosemarie | Female | On medication for 1 to 6 months |
2/22/2022
Condition: Major Depressive Disorder
Overall rating 2.7
Effectiveness
Ease of Use
Satisfaction

Very "foggy" head mood did improve although motivation lacking

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