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3.3 Overall Rating

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Most voted positive review

101 People found this comment helpful

This is honestly the worst drug anyone could ever take. I took 60mg of Duloxetine for over 5 years and had to come off it for surgery. I was initially prescribed it by a psychiatrist and left on it for so long because my GPs didn’t know what it was or what it did. Admittedly, it did the job and helped a lot with my depression and anxiety, but it wasn’t worth it for the withdrawal symptoms I suff...

Shared reviews and ratings

none | 45-54 | Female | On medication for 6 months to less than 1 year | Patient
5/1/2015
Condition: Other
Overall rating 3.0
Effectiveness
Ease of Use
Satisfaction

have fibromialgia and authritis all over lots of other issues too ins wouldnt cover cymbalta so its been duloxitine from the start been about 6 months my anziety is a little better still dont sleep well wierd dreams and lots of pain

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nancy131630 | 45-54 | Female | On medication for 10 years or more | Patient
4/20/2015
Condition: Chronic Muscle or Bone Pain
Overall rating 4.0
Effectiveness
Ease of Use
Satisfaction

The medicine works great, but I've noticed that if I miss a dose, by late morning/early afternoon, I will start getting this whooshing feeling in my ears. Within a couple of hours of making up the dose, the feeling will stop. Has anyone else noticed that?

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Anonymous | 45-54 | Female | On medication for 5 to less than 10 years | Patient
3/18/2015
Condition: Neuropathic Pain
Overall rating 4.0
Effectiveness
Ease of Use
Satisfaction

I take 60mg once a day for neuropathy in my feet. It does help that however we found it also helps with keep me calm. Have been on for at least 8 years. Have tried coming off but I can not sleep. If I miss a dose I can't sleep. I am now taking the generic which is so much more affordable. Not sure if generic is as good but I can afford it.

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rgargus | 65-74 | Male | On medication for 1 to 6 months | Patient
2/24/2015
Condition: Other
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

I had been taking zoloft for anxiety, stress, tension. When I saw that cymbalta had went generic, I asked doctor for generic/duloxetine. I noticed almost immediately the difference. My bedtime, sleepiness changed from going to bed/sleep around 10 PM to now 11 to 12 PM. Also feel as if it has helped my constant pain to a degree. Worked for my needs.

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jenna | 45-54 | Female | On medication for 6 months to less than 1 year | Patient
1/25/2015
Condition: Neuropathic Pain
Overall rating 2.0
Effectiveness
Ease of Use
Satisfaction

this drug did not help me at all, 10kg weight gain and did nothing for pain, been 2 years and i cannot remove the 10kg , tried every diet and even a water diet for 1 week, dont use this drug it is not worth it.

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missanne | 35-44 | Female | Patient
1/5/2015
Condition: Chronic Muscle or Bone Pain
Overall rating 3.0
Effectiveness
Ease of Use
Satisfaction

Seriously look into other alternate drugs before going on this particular drug. My pain was the same as with no medication, bruising was severe, I could not get enough water in my system, and the dizziness/nausea never went away.

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litakilp | 75 or over | Female | On medication for 5 to less than 10 years | Patient
12/31/2014
Condition: Anxiousness associated with Depression
Overall rating 4.0
Effectiveness
Ease of Use
Satisfaction

I don't know how I would feel without this medication. I feel that I am living a normal life -- with only mild ups and downs. I had extreme ones before using this medications.

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loveone | 19-24 | Female | On medication for 1 to 6 months | Patient
10/2/2014
Condition: Other
Overall rating 1.0
Effectiveness
Ease of Use
Satisfaction

Duloxetine was the third anti depression/anxiety medication I have tried. Previously, celexa and prozac, both of which i felt had stopped working after a while. I was given Duloxetine for Major depressive disorder/panic disorder/chronic pain. I would not recommend this drug to ANYONE suffering from depression/anxiety. I was crying over everything from commercials to someone asking me to do something for them and MORE. No reason at all and I would be sobbing hysterically. On top of that I had horribly invasive thoughts, not suicidal, but things like "what would happen if I were to just run the red light instead of stopping?" I physically could not make myself smile because I felt there was no reason in the world to smile at all. Horrible drug, I begged my doctor in tears to take me off it after 6 weeks. Read More Read Less

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Anonymous | 75 or over | Male | On medication for less than 1 month | Patient
8/15/2014
Condition: Disorder characterized by Stiff, Tender & Painful Muscles
Overall rating 2.0
Effectiveness
Ease of Use
Satisfaction

Almost immediate freedom from pain and anxiety. However, the drug was given in combination with Alprazolam and Tramadol. After three days, my wife saw me unconscious, foaming at the mouth and with white eyes. She called 911 and I went to the ER. I have no recall of any of this. Hospitalized for four days. I was told that I was near death.

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mm | 45-54 | Female | On medication for 5 to less than 10 years | Patient
8/13/2014
Condition: Disorder characterized by Stiff, Tender & Painful Muscles
Overall rating 2.0
Effectiveness
Ease of Use
Satisfaction

I had taken Cymbalta for 6 years for fibromyalgia pain, neck injury/spinal pain, and depression. It had worked very well to control my pain better than neurontin or lyrica. When Duloxetine was released, my local pharmacy filled my prescription with it instead of Cymbalta without notifying me. I agreed to try it. I didn't even make it a full month before my neuropathic pain and fibromyalgia pain returned. My doctor changed me immediately back to Cymbalta. I guess some people can take the generic and some can't. I have never had a problem taking generic medications before, but this particular drug is the exception for me. I am a RN and am very knowledgeable about the way medications effect each individual differently. I wish insurance companies understood thisRead More Read Less

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Anonymous | 45-54 | Female | On medication for 1 to 6 months | Patient
8/6/2014
Condition: Major Depressive Disorder
Overall rating 2.7
Effectiveness
Ease of Use
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Les | 65-74 | Male | On medication for less than 1 month | Patient
7/20/2014
Condition: Other
Overall rating 5.0
Effectiveness
Ease of Use
Satisfaction

After taking only 3 doses of this drug, my osteoarthritis and Morton's Neuroma pain have diminished by 80%. I did experience the published shallowness of breath and somewhat lightheadedness after the first 2 doses, but by the 3rd dose this has been minimal.

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Noon | 55-64 | Male | On medication for 2 to less than 5 years | Patient
7/11/2014
Condition: Major Depressive Disorder
Overall rating 4.7
Effectiveness
Ease of Use
Satisfaction

Brand (Lilly) had been better at treating depression related to pain, 30 mg twice per day. Generic (Teva) doesn't seem to manage my depression as well, but Lilly has increased their pricing so I had to switch. Overall, Cymbalta, was prescribed as a dual purpose medication and it's effective enough to deal with both.

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Anonymous | 65-74 | Female | On medication for less than 1 month | Patient
6/16/2014
Condition: Chronic Muscle or Bone Pain
Overall rating 1.7
Effectiveness
Ease of Use
Satisfaction

Rx for Fibromyalgia. Caused severe sweating, intestinal cramps,tiredness.

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Ruff | 75 or over | Male | On medication for 6 months to less than 1 year | Patient
6/16/2014
Condition: Neuropathic Pain
Overall rating 3.0
Effectiveness
Ease of Use
Satisfaction

Some light headiness, dizziness and GI problems.

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Jeff | 45-54 | Male | On medication for 6 months to less than 1 year | Patient
6/14/2014
Condition: Major Depressive Disorder
Overall rating 3.3
Effectiveness
Ease of Use
Satisfaction

I switched from 90mg/day Cymbalta to 90mg/day Duloxetine. The Duloxetine is just not as effective. Duloxetine 90mg feels like Cymbalta 60mg. I suspect the dosage might not be consistent because sometimes I experience symptoms of a missed dose - disturbing vivid dreams and anxiety.

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kathy | 55-64 | Female | On medication for less than 1 month | Patient
6/3/2014
Condition: Neuropathic Pain
Overall rating 1.0
Effectiveness
Ease of Use
Satisfaction

although I am on other meds, this one made me feel like I was on a drug "trip!!!" of some kind. Very sleepy and disoriented after only one 60 mg. capsule. Didn't matter whether it was taken in AM or PM....

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JanLou | 65-74 | Female | On medication for less than 1 month | Patient
6/2/2014
Condition: Chronic Muscle or Bone Pain
Overall rating 3.3
Effectiveness
Ease of Use
Satisfaction

Upon switching from Cymbalta to Duloxetine, I have started experiencing more pain and depression than when taking Cymbalta.

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SpringTX | 55-64 | Female | On medication for less than 1 month | Patient
6/2/2014
Condition: Chronic Muscle or Bone Pain
Overall rating 4.7
Effectiveness
Ease of Use
Satisfaction

I switched to Duloxetine from Naproxen for knee and back pain. Noticable reduced swelling and less pain.

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Angie | 45-54 | Female | On medication for less than 1 month | Patient
5/15/2014
Condition: Major Depressive Disorder
Overall rating 1.3
Effectiveness
Ease of Use
Satisfaction

Taking generic Cymbalta (duloxetine) has made my depression/anxiety much worse. I feel terrible/mental confusion/lack of energy. Does not work for me.

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