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Causes of Epilepsy

Reviewed by Brunilda Nazario, MD on August 25, 2020

 

 

What Are the Causes of Epilepsy?

Epilepsy is a general term for the tendency to have seizures. Epilepsy is usually diagnosed only after a person has had more than one seizure.

When identifiable, the causes of epilepsy usually involve some form of injury to the brain. For most people, though, epilepsy's causes aren't known.

What Are Seizures?

A seizure occurs when a burst of electrical impulses in the brain escape their normal limits. They spread to neighboring areas and create an uncontrolled storm of electrical activity. The electrical impulses can be transmitted to the muscles, causing twitches or convulsions.

Types of Seizures

There are two types of seizures:

Focal seizures. These seizures involve abnormal activity in just one part of your brain. You may lose consciousness, or you may stay alert when you have them. 

  • Without loss of consciousness. These seizures may just change your emotions, or alter your sense of sight, smell, taste, or sound. You might also jerk an arm or a leg without meaning to, or feel tingling, dizziness, or see flashing lights.
  • With loss of consciousness. During these seizures, you aren’t quite aware of your surroundings as usual. You may stare into space, or move repetitively by chewing, rubbing your hands, or walking in circles.

Generalized seizures. This type of seizure tends to involve all the parts of your brain. There are six kinds of generalized seizures:

  • Absence seizures happen mostly in children and involve small movements such as lip smacking or eye blinking.
  • Tonic seizures make you stiffen the muscles in your arms, legs, back and sometimes fall down as a result.
  • Atonic seizures take away your muscle control. They’re also called drop seizures, because they can make you collapse onto the floor.
  • Clonic seizures often make you repeat jerking movements in your neck, face, and arms.
  • Myoclonic seizures involve short, twitching and jerking motions in your arms and legs.
  • Tonic-clonic seizures, which used to be called grand-mal seizures, can make you lose consciousness, stiffen your whole body, and shake. You may also bite your tongue or lose control of your bladder.

Causes of Epilepsy

There are around 180,000 new cases of epilepsy each year. About 30% occur in children. Children and elderly adults are the ones most often affected.

There is a clear cause for epilepsy in only a minority of the cases. Typically, the known causes of seizure involve some injury to the brain. Some of the main causes of epilepsy include:

  • Low oxygen during birth
  • Head injuries that occur during birth or from accidents during youth or adulthood
  • Brain tumors
  • Genetic conditions that result in brain injury, such as tuberous sclerosis
  • Infections such as meningitis or encephalitis
  • Stroke or any other type of damage to the brain
  • Abnormal levels of substances such as sodium or blood sugar
  • Developmental disorders, such as autism and neurofibromatosis
  • Injury before birth, such as brain damage from an infection in the mother, poor nutrition or oxygen deficiencies

In up to 70% of all cases of epilepsy in adults and children, no cause can be discovered.

Causes of Seizures

Although the underlying causes of epilepsy are usually not known, certain factors are known to provoke seizures in people with epilepsy. Avoiding these triggers can help you avoid seizures and live better with epilepsy:

  • Missing medication doses
  • Heavy alcohol use
  • Cocaine, ecstasy, or other illegal drugs
  • Lack of sleep
  • Other medicines that interfere with seizure medications
  • Flashing lights, images, and repetitive patterns may cause seizures in persons with photosensitive seizure disorder.

For about 1 in 2 women with epilepsy, seizures tend to occur more around the time of menstrual periods. Changing or adding certain drugs before menstrual periods can help.

WebMD Medical Reference

Sources

SOURCES:

Epilepsy.com: "What Causes Epilepsy?"

Epilepsy Foundation: "Causes."

Mayo Clinic: “Epilepsy.”

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