Young Women Face Risk After Heart Attack, Stroke

Odds of another life-threatening event are much higher than normal, study says

From the WebMD Archives

By Dennis Thompson

HealthDay Reporter

MONDAY, Nov. 23, 2015 (HealthDay News) -- Young women who survive a heart attack or stroke may not be out of danger once they recover, European researchers say.

These women could continue to face drastically increased risk of death -- or another heart attack or stroke -- for a long time after their initial life-threatening illness, according to a new study published Nov. 23 in JAMA Internal Medicine.

"Our results show that the increase in risk is persistent over a long time, making it even more clear that women should keep their regular checkups and try to maintain a healthy lifestyle, even if their first event was years ago," said co-author Bob Siegerink, group leader of epidemiology at the Charite Center for Stroke Research in Berlin, Germany.

Overall death rates are 3.7 times higher in women who've had a heart attack and 1.8 times higher in women who've had a stroke, compared with healthy women, researchers found.

Women who've had a heart attack will have a 20-times increased risk of a second heart attack, and a tripled risk of a first stroke, according to findings.

At the same time, female stroke victims will have an 18-fold increased risk of another stroke and an almost six times greater risk of a first heart attack.

Researchers based these findings on 226 women who had a heart attack, 160 women who had a stroke and 782 healthy women. All live in the Netherlands. The heart attack and stroke patients were about 40 years old on average at the time of their health event. They were followed for a median of almost 19 years -- half more than that, half less.

Siegerink noted that the women were most likely to suffer a second occurrence of whatever struck them the first time, be it a heart attack or a stroke.

"Basically, the long-term risk of cardiovascular events are 'true to type', which is an indication that the mechanisms that lead to cardiovascular recurrence are disease-specific," he said.

These results show that young women need to take their heart health more seriously, particularly if they've had a heart attack or stroke, said Dr. Suzanne Steinbaum, director of Women's Heart Health at Lenox Hill Hospital in New York City.

Heart disease is the leading cause of death for women in the United States, killing nearly 422,000 each year, according to the U.S. Centers for Disease Control and Prevention.

"If a young woman has a cardiovascular event, there needs to be aggressive secondary prevention to make sure this never happens again, because the risk of dying is so much higher for her," Steinbaum said.

Preventive measures may include controlling blood pressure, reducing cholesterol and blood sugar levels, eating healthy, exercising, quitting smoking and cutting back on alcohol consumption, said Steinbaum and Dr. Nieca Goldberg, medical director of the NYU Langone Joan H. Tisch Center for Women's Health in New York City.

"When heart attacks happen to younger women and they feel better, it's good they get back to their normal lives but they have to be mindful of prevention throughout their life," said Goldberg, who also is a spokeswoman for the American Heart Association.

In a way, these results aren't news. Researchers have long known that anyone who has a heart attack or stroke is at increased risk of another one, compared with people who've never had one, Goldberg said.

But young women pursuing a career and raising a family often put themselves last in line for medical care, said Dr. Carl Pepine, a professor of cardiovascular medicine at the University of Florida College of Medicine.

These women may not realize that they are at risk for a heart attack or stroke, or they might shrug off that risk as they get the kids off to school or prepare for a busy work day, said Pepine, a past president of the American College of Cardiology and a member of its Cardiovascular Disease in Women Committee.

"Young women are not free of cardiovascular disease, and when they have an event they are at heightened risk of bad things happening over the long term," he said. "Women need to understand that they have to put themselves ahead of other obligations, and protect their heart health."

Show Sources

SOURCES: Bob Siegerink, Ph.D., group leader, epidemiology, the Charite Center for Stroke Research, Berlin, Germany; Dr. Suzanne Steinbaum, M.D., director, Women's Heart Health, Lenox Hill Hospital, New York City; Nieca Goldberg, M.D., medical director, NYU Langone Joan H. Tisch Center for Women's Health, New York City; Carl Pepine, professor, cardiovascular medicine, University of Florida College of Medicine, Gainesville, Fla.; Nov. 23, 2015, JAMA Internal Medicine

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