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Allergic Reaction Causes

Almost anything can trigger an allergic reaction.

  • The body's immune system has a patrol of white blood cells, which produce antibodies.

    • When the body is exposed to an antigen, a complex set of reactions begins.

    • The white blood cells produce an antibody specific to that antigen. This is called "sensitization."

    • The job of the antibodies is to detect and destroy substances that cause disease and sickness. In allergic reactions, the antibody is called immunoglobulin E, or IgE.

  • This antibody promotes production and release of chemicals and hormones called "mediators."

    • Histamine is one well-known mediator.

    • Mediators have effects on local tissue and organs in addition to activating more white blood cell defenders. It is these effects that cause the symptoms of the reaction.

    • If the release of the mediators is sudden or extensive, the allergic reaction may also be sudden and severe.

  • Your allergic reactions are unique to you. For example, your body may have learned to be allergic to poison ivy from repeated exposure.

  • Most people are aware of their particular allergy triggers and reactions.

    • Certain foods, vaccines and medications, latex rubber, aspirin, shellfish, dust, pollen, mold, animal dander, and poison ivy are famous allergens.

    • Bee stings, fire ant stings, penicillin, and peanuts are known for causing dramatic reactions that can be serious and involve the whole body.

    • Minor injuries, hot or cold temperatures, exercise, or even emotions may be triggers.

    • Often, the specific allergen cannot be identified unless you have had a similar reaction in the past.

  • Allergies and the tendency to have allergic reactions run in some families. You may have allergies even if they do not run in your family.

  • Many people who have one trigger tend to have other triggers as well.

  • People with certain medical conditions are more likely to have allergic reactions.

WebMD Medical Reference from eMedicineHealth

Edited on September 02, 2005
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