Find Information About:

Drugs & Supplements

Get information and reviews on prescription drugs, over-the-counter medications, vitamins, and supplements. Search by name or medical condition.

Pill Identifier

Pill Identifier

Having trouble identifying your pills?

Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill.

Get Started
My Medicine

My Medicine

Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.

Get Started

WebMD Health Experts and Community

Talk to health experts and other people like you in WebMD's Communities. It's a safe forum where you can create or participate in support groups and discussions about health topics that interest you.

  • Second Opinion

    Second Opinion

    Read expert perspectives on popular health topics.

  • Community


    Connect with people like you, and get expert guidance on living a healthy life.

Got a health question? Get answers provided by leading organizations, doctors, and experts.

Get Answers

Sign up to receive WebMD's award-winning content delivered to your inbox.

Sign Up

Arthritis Health Center

Font Size

Knee, Hip Replacements Carry Blood Clot Risk

Study: About 1 in 100 Knee Replacement Patients Will Develop a Blood Clot Before Leaving the Hospital
WebMD Health News
Reviewed by Laura J. Martin, MD

Jan. 17, 2012 -- Doctors have long known that dangerous blood clots can occur after joint replacement surgery of the knees or hips.

Now, a new analysis puts numbers on the risk.

About 1 in 100 patients who undergo knee replacement surgery and 1 in 200 patients who have hip replacement surgery will develop a blood clot called venous thromboembolism before leaving the hospital.

"Actual rates in hospitals might indeed be higher," says researcher Jean-Marie Januel, PhD, MPH, RN, senior researcher at the Institute of Social and Preventive Medicine at the University Hospital of Lausanne in Switzerland. The new figures were estimates after Januel and his team evaluated the results of 47 published studies on blood clot risks after joint replacement surgery.

"Actual rates in hospitals should be monitored and made available to patients," Januel tells WebMD.

The new report is published in the Journal of the American Medical Association.

The new estimates may not reflect the true risk of blood clots, according to two doctors familiar with the new analysis. That is because the blood clot risk persists beyond the study period, they tell WebMD.

Orthopaedic Surgery and Blood Clot Risk

Knee replacement surgery and hip replacement surgery are done to repair arthritic or injured joints. The number of these surgeries has increased in recent years. The surgeries are also being done on younger patients.

About 230,000 hip replacement surgeries were done in 2007, according to the CDC. More than 600,000 knee replacement surgeries were done in 2009, according to the Agency for Healthcare Research and Quality. Blood clots after the surgeries can occur in the deep veins of the legs or elsewhere. They often occur without symptoms. Some of these clots can travel to the lungs.

Doctors routinely prescribe anti-clotting drugs for the patients to help prevent blood clots from forming after the surgical procedure. However, they cannot prevent all clots.

Risk of Blood Clots After Hip, Knee Surgery

Januel's team researched the medical literature to find studies that assessed the risk of blood clots after knee replacement or hip replacement surgery. They focused on studies that looked at clots that occurred before leaving the hospital.

1 | 2 | 3

Today on WebMD

Mature woman exercise at home
Hint: Warming up first is crucial.
feet with gout
Quiz yourself.
woman in pain
One idea? Eat fish to curb inflammation.
senior couple walking
Can you keep your RA from progressing?
xray of knees with osteoarthritis
close up of man wearing dress shoes
feet with gout
close up of red shoe in shoebox
two male hands
Woman massaging her neck
5 Lupus Risk Factors