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    Reactive Arthritis

    Important
    It is possible that the main title of the report Reactive Arthritis is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.

    Synonyms

    Disorder Subdivisions

    • None

    General Discussion

    Reactive arthritis is a general term for a form of joint inflammation (arthritis) that develops as a "reaction" to an infection in another area of the body (i.e., outside of the joints). Joint inflammation is characterized by redness, swelling, pain and warmth in and around the affected joint. In reactive arthritis, the large joints of the lower limbs and the sacroiliac joints are most often affected. Two other common symptoms of reactive arthritis are inflammation of the urinary tract and inflammation of the membrane (conjunctiva) that lines the eyelids (conjunctivitis). These three characteristic symptoms may occur separately, all at once or not at all. Additional symptoms such as fever, weight loss, lower back pain and heel pain may also occur. Reactive arthritis usually develops following a bout with certain bacterial infections including Chlamydia, Salmonella, Shigella, Yersinia, and Campylobacter.

    Reactive arthritis belongs to a group of related disorders known as the spondyloarthropathies. These disorders are linked by the association of similar symptoms and a specific genetic marker called HLA-B27. Symptoms common to these disorders include arthritis, especially of the lower limbs, lower back pain and enthesitis, a condition characterized by inflammation at the spot where skeletal muscle attaches to bone. This group of disorders includes reactive arthritis, ankylosing spondylitis, psoriatic arthritis, undifferentiated spondyloarthritis and spondyloarthritis associated with inflammatory bowel disease.

    Reactive arthritis is a poorly defined disorder that has been described in the medical literature under many different names. No precise diagnostic or classification criteria have been developed that are universally agreed upon in the medical community.

    Resources

    Spondylitis Association of America
    P.O. Box 5972
    Sherman Oaks, CA 91413
    USA
    Tel: (818)892-1616
    Fax: (818)892-1611
    Tel: (800)777-8189
    Email: info@spondylitis.org
    Internet: http://www.spondylitis.org

    American Autoimmune Related Diseases Association, Inc.
    22100 Gratiot Ave.
    Eastpointe, MI 48021
    Tel: (586)776-3900
    Fax: (586)776-3903
    Tel: (800)598-4668
    Email: aarda@aarda.org
    Internet: http://www.aarda.org/

    Arthritis Foundation
    1330 West Peachtree Street, Suite 100
    Atlanta, GA 30309
    USA
    Tel: (404)872-7100
    Tel: (800)283-7800
    Email: arthritisfoundation@arthritis.org
    Internet: http://www.arthritis.org

    Sexuality Information and Education Council of the U.S.
    90 John St.
    Suite 704
    New York, NY 10038
    Tel: (212)819-9770
    Fax: (212)819-9776
    Email: pmalone@siecus.org
    Internet: http://www.siecus.org

    Centers for Disease Control and Prevention
    1600 Clifton Road NE
    Atlanta, GA 30333
    Tel: (404)639-3534
    Tel: (800)232-4636
    TDD: (888)232-6348
    Email: cdcinfo@cdc.gov
    Internet: http://www.cdc.gov/

    Arthritis Society
    393 University Avenue
    Suite 1700
    Toronto
    Ontario, M5G IE6
    Canada
    Tel: 4169797228
    Fax: 4169798366
    Tel: 8003211433
    Email: info@arthritis.ca
    Internet: http://www.arthritis.ca

    NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases
    Information Clearinghouse
    One AMS Circle
    Bethesda, MD 20892-3675
    USA
    Tel: (301)495-4484
    Fax: (301)718-6366
    Tel: (877)226-4267
    TDD: (301)565-2966
    Email: NIAMSinfo@mail.nih.gov
    Internet: http://www.niams.nih.gov/

    Ocular Immunology and Uveitis Foundation
    5 Cambridge Center
    8th Floor
    Cambridge, MA 02142
    Tel: (617)621-6377
    Fax: (781)431-2042
    Tel: (866)353-6377
    Email: fosters@comcast.net
    Internet: http://www.uveitis.org

    Genetic and Rare Diseases (GARD) Information Center
    PO Box 8126
    Gaithersburg, MD 20898-8126
    Tel: (301)251-4925
    Fax: (301)251-4911
    Tel: (888)205-2311
    TDD: (888)205-3223
    Internet: http://rarediseases.info.nih.gov/GARD/

    Madisons Foundation
    PO Box 241956
    Los Angeles, CA 90024
    Tel: (310)264-0826
    Fax: (310)264-4766
    Email: getinfo@madisonsfoundation.org
    Internet: http://www.madisonsfoundation.org

    Autoimmune Information Network, Inc.
    PO Box 4121
    Brick, NJ 08723
    Fax: (732)543-7285
    Email: autoimmunehelp@aol.com

    KickAS.org
    11688 North Sage Brook Road
    Oro Valley, AZ 85737-7342
    Tel: (520)544-3023
    Fax: (520)544-3023
    Email: kickas@gmail.com
    Internet: http://www.kickas.org

    For a Complete Report:

    This is an abstract of a report from the National Organization for Rare Disorders (NORD). A copy of the complete report can be downloaded free from the NORD website for registered users. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational therapies (if available), and references from medical literature. For a full-text version of this topic, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".

    The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.

    It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report

    This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

    For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email orphan@rarediseases.org

    Last Updated: 3/19/2013
    Copyright 1986, 1994, 1997, 1999, 2007, 2009, 2010, 2013 National Organization for Rare Disorders, Inc.

    WebMD Medical Reference from the National Organization for Rare Disorders

    Last Updated: May 28, 2015
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.

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