How It Works
An epidural steroid injection (ESI) is a
combination of a
corticosteroid with a local anesthetic pain relief
medicine. Corticosteroids are strong anti-inflammatory medicines used to
relieve pain. The local anesthetic medicine helps give you immediate pain
relief. Corticosteroid medicines take longer to have an effect.
spinal canal , an ESI is injected into the space around the spinal cord and
nerve roots (epidural space). The injection does not go into the membrane
(thecal sac) that contains the spinal cord and nerve roots.
sometimes are used to treat pain and inflammation from pressure on the spinal
cord. ESI is usually not tried unless symptoms caused by lumbar
spinal stenosis have not responded to other
Imaging tests, such as magnetic resonance
imaging (MRI) or computed tomography (CT) scans, are usually done before you are given the
injection. These tests are used to identify the exact location where nerve
roots are being squeezed. During the injection, an X-ray machine (fluoroscope)
is often used to guide placement of the needle.
Why It Is Used
An epidural steroid injection (ESI)
may be tried when other nonsurgical treatments have failed to relieve severe
leg pain from lumbar spinal stenosis.
The corticosteroids in an
ESI can help provide relief from leg pain by reducing swelling and
inflammation. Local anesthetics help relieve pain but
do not reduce inflammation. Lidocaine can also help relieve pain quickly,
before the corticosteroid has taken effect.
How Well It Works
Lumbar spinal stenosis may cause pain
that radiates from the lower spine to the hips or down a leg. Epidural steroid
injections (ESIs) are used for leg pain rather than back pain from lumbar
Steroid injections can help relieve pain for a short time (2 to 3 weeks) in some people. Experts do not know how well injections work over longer periods of time.1 Some people get enough pain relief that they
can delay or no longer need surgery.2
These injections may relieve symptoms and reduce inflammation but do not
cure spinal stenosis.
Epidural steroid injections (ESIs) should
be used with caution. This treatment may only relieve symptoms for a short
time, and the long-term effects are not well studied. Most experts recommend
that no more than 3 ESIs be given in a 12-month period. Doctors usually wait at least 2 months between injections. And they do not usually give more than 3 or 4 injections into one area.
effects occur, they are usually minor and may include:
- About 2 to 4 days of back pain and tenderness
where the injection was given.
- Feeling sick to your stomach and
More serious side effects are very rare but can include
bleeding, infection, nerve root injury, and
People who have an increased
risk for infections, such as those with
diabetes or those with
immune system problems, may be at a higher risk for
problems from ESIs. People with mental health disorders may also have a higher
risk for problems from this treatment.
See Drug Reference for a
full list of side effects. (Drug Reference is not available in all
What To Think About
Epidural steroid injections (ESIs)
should not be given if there is any sign of infection.
only relieve symptoms for a short time. The long-term effects are not well
studied. Talk with your doctor about the risks related to the number of ESIs
you expect to get.
If lumbar spinal stenosis is caused by a
congenitally (from birth) small spinal column, rather than by
osteoarthritis or another degenerative bone or joint
condition, corticosteroid injections may increase symptoms, such as pain and
Complete the new medication information form (PDF)(What is a PDF document?) to help you understand this medication.
North American Spine Society (2007). Diagnosis and treatment of degenerative lumbar spinal stenosis: Evidence-based clinical guidelines for multidisciplinary spine care. Available online: http://www.spine.org/Documents/NASSCG_Stenosis.pdf.
Isaac Z, et al. (2005). Lumbar spinal stenosis. In WJ
Koopman, ed., Arthritis and Allied Conditions: A Textbook of Rheumatology, 15th ed., vol. 2, pp. 2087-2092. Philadelphia: Lippincott
Williams and Wilkins.