Synthetic Wrinkle Fillers
This smaller category of wrinkle fillers includes lab-made substances that are not related to anything found naturally in the skin.
All the fillers in this group have similar side effects, such as redness, swelling, or bruising at the site of the injection. Other side effects include nodules or bumps under the skin that can be seen and felt and that, in rare instances, may require surgery to remove.
The benefits include a longer-lasting effect. And at least one filler offers permanent filling of lines and creases. Remember, products with longer-lasting effects are more likely to cause side effects. And when not used correctly, synthetic wrinkle fillers may cause disfigurement.
Synthetic wrinkle fillers include:
Collagen Wrinkle Fillers
Scientists made the first wrinkle fillers from a purified form of collagen extracted mostly from cows. Although it worked well and offered a natural-looking fill, the results didn't last long. Most collagen injections began to break down as early as 1 month after treatment. Because these wrinkle fillers were made from an animal source, they also had a higher rate of allergic reaction and required allergy testing beforehand.
New ways of processing the collagen have helped lower the risks. Plus, new forms of synthetic collagens are making these injections safer and more useful to a wider range of people. Although the results don't last as long as other wrinkle fillers, many believe the results are more natural looking.
Side effects of collagen injections include some risk of allergic reaction (mostly for those still using cow sources), as well as bruising and redness at the site of the injection.
Collagen injections include: