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    Endometrial Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Treatment Options by Stage

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    Stage III Endometrial Cancer

    Treatment of stage III endometrial cancer may include the following:

    • Surgery (radical hysterectomy and removal of lymph nodes in the pelvis so they can be viewed under a microscope to check for cancer cells) followed by adjuvant chemotherapy and/or radiation therapy.
    • Chemotherapy combined with internal and external radiation therapy for patients who cannot have surgery.
    • Hormone therapy for patients who cannot have surgery or radiation therapy.
    • Combination chemotherapy with or without biologic therapy.
    • Clinical trials of new types of treatment.

    Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage III endometrial carcinoma. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. Talk with your doctor about clinical trials that may be right for you. General information about clinical trials is available from the NCI Web site.

    Stage IV Endometrial Cancer

    Treatment of stage IV endometrial cancer may include the following:

    • Surgery followed by chemotherapy and/or radiation therapy.
    • Internal and external radiation therapy for patients who cannot have surgery.
    • Hormone therapy for patients whose cancer has spread to distant parts of the body (such as the lungs).
    • Combination chemotherapy with or without biologic therapy.
    • Clinical trials of targeted therapy.
    • Clinical trials of chemotherapy.

    Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage IV endometrial carcinoma. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. Talk with your doctor about clinical trials that may be right for you. General information about clinical trials is available from the NCI Web site.

    This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http:// cancer .gov or call 1-800-4-CANCER.

    WebMD Public Information from the National Cancer Institute

    Last Updated: May 28, 2015
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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