The pancreas is an organ located behind your stomach next to the top of the small intestine. It is about six inches long but is less than 2 inches wide and functions as two separate organs. It has two big manufacturing jobs in the body:
It makes digestive juices that help the intestines break down food.
It produces hormones -- including insulin -- that regulate the body's use of sugars and starches.
The pancreas is divided into three sections: the head, the body, and the tail.
Initially, pancreatic cancer tends to be silent and painless as it grows. By the time it's large enough to cause symptoms, pancreatic cancer has generally grown outside the pancreas. At this point, symptoms depend on the cancer's location within the pancreas:
Pancreatic cancer in the body or tail of the pancreas usually causes belly and/or back pain and weight loss.
In general, symptoms appear earlier from cancers in the head of the pancreas, compared to those in the body and tail.
Pancreatic Cancer and Gastrointestinal Symptoms
Because pancreatic cancer grows around important areas of the digestive system, gastrointestinal symptoms often predominate:
Abdominal pain. More than 80% of people with pancreatic cancer eventually experience some abdominal pain as the tumor grows. Pancreatic cancer can cause a dull ache in the upper abdomen radiating to the back. The pain may come and go.
Bloating. Some people with pancreatic cancer have a sense of early fullness with meals (satiety) or an uncomfortable swelling in the abdomen.
Pale-colored stools. If the duct draining bile into the intestine is blocked by pancreatic cancer, the stools may lose their brown color and become pale or clay-colored. Urine may become darker.
Pancreatic Cancer: Whole-Body Symptoms
As it grows and spreads, pancreatic cancer affects the whole body. Such symptoms can include:
Loss of appetite
Elevated blood sugars. Some people with pancreatic cancer develop diabetes as the cancer impairs the pancreas' ability to produce insulin. (However, the vast majority of people with a new diagnosis of diabetes do not have pancreatic cancer.)