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Cellular Classification of Adult Primary Liver Cancer

    Malignant tumors of the liver are primarily adenocarcinomas, with two major cell types: hepatocellular and cholangiocarcinoma.

    Histologic classification is as follows:

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    Unresectable Primary Gastrointestinal Stromal Tumors

    Therapy with neoadjuvant imatinib is under evaluation. It may be used for patients with very large primary gastrointestinal stromal tumors (GIST) or poorly positioned small GIST (considered unresectable without the risk of unacceptable morbidity or functional deficit) until surgical therapy is feasible, which can take as long as 6 to 12 months.[1,2] There are no controlled trials addressing the benefits of imatinib in this setting, so the impact of neoadjuvant imatinib on overall survival (OS) is...

    Read the Unresectable Primary Gastrointestinal Stromal Tumors article > >

    • Hepatocellular carcinoma (liver cell carcinoma).
    • Hepatocellular carcinoma (fibrolamellar variant). The fibrolamellar variant is important because an increased proportion of these patients may be cured if the tumor can be resected. It is more frequent in young women. It also generally exhibits a slower clinical course than the more common hepatocellular carcinoma.
    • Cholangiocarcinoma (intrahepatic bile duct carcinoma).
    • Mixed hepatocellular cholangiocarcinoma.
    • Undifferentiated.

    Hepatoblastoma rarely occurs in adults.

      WebMD Public Information from the National Cancer Institute

      Last Updated: February 25, 2014
      This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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