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Nausea and Vomiting (PDQ®): Supportive care - Health Professional Information [NCI] - Acute / Delayed Nausea and Vomiting (Emesis) Etiology

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Delayed N&V

Delayed (or late) N&V occurs more than 24 hours after chemotherapy administration. Delayed N&V is associated with cisplatin, cyclophosphamide, and other drugs (e.g., doxorubicin and ifosfamide) given at high doses or given on 2 or more consecutive days.

  • Etiologies:
    • Patients who experience acute emesis with chemotherapy are significantly more likely to have delayed emesis.
  • Risk factors:
    • All predicative characteristics for acute emesis should be considered risk factors for delayed emesis.
  • Emetic classifications:
    • Refer to the Acute Nausea and Vomiting (Emesis) (N&V) section of this summary for more information.

References:

  1. Grunberg SM, Deuson RR, Mavros P, et al.: Incidence of chemotherapy-induced nausea and emesis after modern antiemetics. Cancer 100 (10): 2261-8, 2004.
  2. Cohen L, de Moor CA, Eisenberg P, et al.: Chemotherapy-induced nausea and vomiting: incidence and impact on patient quality of life at community oncology settings. Support Care Cancer 15 (5): 497-503, 2007.
  3. Kris MG, Hesketh PJ, Somerfield MR, et al.: American Society of Clinical Oncology guideline for antiemetics in oncology: update 2006. J Clin Oncol 24 (18): 2932-47, 2006.
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WebMD Public Information from the National Cancer Institute

Last Updated: February 25, 2014
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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