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Treating Tuberculosis in Children - Topic Overview

Treatment of active tuberculosis (TB) in children is usually different from treatment of TB in adults. In children younger than 4 years, TB is more likely to spread beyond the lungs (extrapulmonary TB). It is also harder to get from children a sputum sample that grows TB bacteria.1 So the doctor may assume that a child is infected with the same type of TB bacteria as the person who most likely infected him or her.

In general, TB treatment in children usually begins with 3 medicines instead of 4 because:

  • The number of bacteria usually is small.
  • It may be hard to determine if a child is having vision problems, which can be caused by ethambutol.

Children with TB usually take isoniazid, rifampin, and pyrazinamide for 2 months. Treatment then continues for at least 4 more months with isoniazid and rifampin. Vitamin B6 (pyridoxine) also may be recommended during TB treatment if the child is not eating a good diet or isn't getting enough nutrients. Directly observed therapy (DOT) is usually done to make sure that the child takes all of the medicine.

Additional medicines taken for a longer time may be needed for children:

  • With extrapulmonary TB.
  • Who are infected with TB and human immunodeficiency virus (HIV).
  • Who are infected with TB bacteria that cannot be killed by 1 or more antibiotics.

A child taking ethambutol to treat a TB infection should have his or her vision checked every month.

    This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http:// cancer .gov or call 1-800-4-CANCER.

    WebMD Medical Reference from Healthwise

    Last Updated: April 04, 2013
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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