Skip to content

    Colorectal Cancer Health Center

    Medical Reference Related to Colorectal Cancer

    1. Colorectal Cancer Prevention (PDQ®): Prevention - Health Professional Information [NCI] - Description of the Evidence

      BackgroundIncidence and mortalityColorectal cancer (CRC) is the third most common malignant neoplasm worldwide [1] and the second leading cause of cancer deaths (irrespective of gender) in the United States.[2] It is estimated that there will be 142,820 new cases diagnosed in the United States in 2013 and 50,830 deaths due to this disease.[2] Between 2005 and 2009, CRC incidence rates in the United States declined by 4.1% per year among adults aged 50 years and older.[2] For the past 20 years, the mortality rate has been declining in both men and women. Between 2005 and 2009, the mortality rate declined by 2.4% per year in men and by 3.1% per year in women. In adults younger than 50 years, CRC incidence rates increased by about 1.1% per year.[2] The overall 5-year survival rate is 64%. About 5% of Americans are expected to develop the disease

    2. Colorectal Cancer, Metastatic or Recurrent - nci_ncicdr0000062753-nci-header

      This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http://cancer.gov or call 1-800-4-CANCER.Colorectal Cancer Screening

    3. Colorectal Cancer Prevention (PDQ®): Prevention - Health Professional Information [NCI] - Colorectal Cancer Prevention

      Avoiding risk factors and increasing protective factors may help prevent cancer.Avoiding cancer risk factors may help prevent certain cancers. Risk factors include smoking, being overweight, and not getting enough exercise. Increasing protective factors such as quitting smoking, eating a healthy diet, and exercising may also help prevent some cancers. Talk to your doctor or other health care professional about how you might lower your risk of cancer.The following risk factors increase the risk of colorectal cancer:AgeThe risk of colorectal cancer increases after age 50. Most cases of colorectal cancer are diagnosed after age 50.Family history of colorectal cancerHaving a parent, brother, sister, or child with colorectal cancer doubles a person's risk of colorectal cancer.Personal historyHaving a personal history of inflammatory bowel disease increases the risk of colorectal cancer. Inherited riskThe risk of colorectal cancer is increased when certain gene changes linked to familial

    4. Rectal Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Stage I Colon Cancer Treatment

      Because of its localized nature, stage I colon cancer has a high cure rate.Standard Treatment Options for Stage I Colon CancerSurgeryStandard treatment options for stage I colon cancer include the following:Wide surgical resection and anastomosis.Evidence (laparoscopic techniques):The role of laparoscopic techniques [1,2,3,4] in the treatment of colon cancer was examined in a multicenter, prospective, randomized trial (NCCTG-934653, now closed) comparing laparoscopic-assisted colectomy (LAC) with open colectomy.Three-year recurrence rates and 3-year overall survival rates were similar in the two groups. (Refer to the Primary Surgical Therapy section in the Treatment Option Overview section of this summary for more information.)The quality-of-life component of this trial has been published and minimal short-term quality-of-life benefits with LAC were reported.[5][Level of evidence: 1iiC]Current Clinical TrialsCheck for U.S. clinical trials from NCI's list of cancer clinical trials

    5. Rectal Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Treatment Option Overview for Colon Cancer

      Table 6. Standard Treatment Options for Stages 0–III Colon CancerStage (TNM Staging Criteria)Standard Treatment OptionsStage 0 Colon CancerSurgeryStage I Colon CancerSurgeryStage II Colon CancerSurgeryStage III Colon CancerSurgery Adjuvant chemotherapyTable 7. Treatment Options for Stage IV and Recurrent Colon CancerStage (TNM Staging Criteria)Treatment OptionsTreatment of Liver MetastasisSurgeryNeoadjuvant chemotherapyLocal ablationAdjuvant chemotherapyIntra-arterial chemotherapyTreatment of Stage IV and Recurrent Colon CancerSurgeryChemotherapy and targeted therapySecond-line chemotherapyPrimary Surgical TherapyStandard treatment for patients with colon cancer has been open surgical resection of the primary and regional lymph nodes for localized disease.The role of laparoscopic techniques [1,2,3,4] in the treatment of colon cancer has been examined in two studies.Evidence (laparoscopic techniques):A multicenter, prospective, randomized, noninferiority trial

    6. Rectal Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Colorectal Cancer Screening

      Tests are used to screen for different types of cancer.Some screening tests are used because they have been shown to be helpful both in finding cancers early and decreasing the chance of dying from these cancers. Other tests are used because they have been shown to find cancer in some people; however, it has not been proven in clinical trials that use of these tests will decrease the risk of dying from cancer. Scientists study screening tests to find those with the fewest risks and most benefits. Cancer screening trials also are meant to show whether early detection (finding cancer before it causes symptoms) decreases a person's chance of dying from the disease. For some types of cancer, finding and treating the disease at an early stage may result in a better chance of recovery. Clinical trials that study cancer screening methods are taking place in many parts of the country. Information about ongoing clinical trials is available from the NCI Web site.Studies show that screening for

    7. Colorectal Cancer, Metastatic or Recurrent - nci_ncicdr0000062959-nci-header

      This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http://cancer.gov or call 1-800-4-CANCER.Rectal Cancer Treatment

    8. Lynch Syndrome

      Important It is possible that the main title of the report Lynch Syndromes is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. ...

    9. Rectal Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Stage Information for Colon Cancer

      Treatment decisions should be made with reference to the TNM classification [1] rather than to the older Dukes or the Modified Astler-Coller classification schema.The American Joint Committee on Cancer (AJCC) and a National Cancer Institute–sponsored panel recommended that at least 12 lymph nodes be examined in patients with colon and rectal cancer to confirm the absence of nodal involvement by tumor.[2,3,4] This recommendation takes into consideration that the number of lymph nodes examined is a reflection of the aggressiveness of lymphovascular mesenteric dissection at the time of surgical resection and the pathologic identification of nodes in the specimen. Retrospective studies demonstrated that the number of lymph nodes examined in colon and rectal surgery may be associated with patient outcome.[5,6,7,8]AJCC Stage Groupings and TNM DefinitionsThe AJCC has designated staging by TNM classification to define

    10. Rectal Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Risks of Colorectal Cancer Screening

      Screening tests have risks.Decisions about screening tests can be difficult. Not all screening tests are helpful and most have risks. Before having any screening test, you may want to discuss the test with your doctor. It is important to know the risks of the test and whether it has been proven to reduce the risk of dying from cancer.False-negative test results can occur.Screening test results may appear to be normal even though colorectal cancer is present. A person who receives a false-negative test result (one that shows there is no cancer when there really is) may delay seeking medical care even if there are symptoms.False-positive test results can occur.Screening test results may appear to be abnormal even though no cancer is present. A false-positive test result (one that shows there is cancer when there really isn't) can cause anxiety and is usually followed by more tests (such as biopsy), which also have risks.The following colorectal cancer screening tests have risks:Fecal

    Displaying 91 - 100 of 211 Articles << Prev Page 6 7 8 9 10 11 12 13 14 15 Next >>

    Today on WebMD

    Colorectal cancer cells
    The right diagnosis is the most important factor.
    man with a doctor
    Our health check will steer you in the right direction.
     
    sauteed cherry tomatoes
    Fight cancer one plate at a time.
    doctor and patient
    Colorectal Cancer Therapy
     
    bread
    ARTICLE
    Colon vs Rectal Cancer
    VIDEO
     
    New Colorectal Treatments
    VIDEO
    can lack of sleep affect your immune system
    FEATURE
     
    Cancer Facts Quiz
    QUIZ
    Virtual Colonoscopy
    VIDEO
     
    Picture of the Colon
    ANATOMY
    Vitamin D
    SLIDESHOW