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Colorectal Cancer Health Center

Medical Reference Related to Colorectal Cancer

  1. Colon Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - To Learn More About Colon Cancer

    For more information from the National Cancer Institute about colon cancer, see the following:Colon and Rectal Cancer Home PageWhat You Need to Know About™ Cancer of the Colon and RectumColorectal Cancer PreventionColorectal Cancer ScreeningTests to Detect Colorectal Cancer and PolypsUnusual Cancers of ChildhoodCryosurgery in Cancer Treatment: Questions and AnswersDrugs Approved for Colon CancerTargeted Cancer TherapiesUnderstanding Cancer Series: Targeted Therapies (Advances in Targeted Therapies)Genetic Testing for Hereditary Cancer SyndromesFor general cancer information and other resources from the National Cancer Institute, see the following:What You Need to Know About™ CancerUnderstanding Cancer Series: CancerCancer StagingChemotherapy and You: Support for People With CancerRadiation Therapy and You: Support for People With CancerCoping with Cancer: Supportive and Palliative CareQuestions to Ask Your Doctor About CancerCancer LibraryInformation For

  2. Colorectal Cancer Prevention (PDQ®): Prevention - Health Professional Information [NCI] - Changes to This Summary (09 / 27 / 2013)

    The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.Editorial changes were made to this summary.This summary is written and maintained by the PDQ Screening and Prevention Editorial Board, which is editorially independent of NCI. The summary reflects an independent review of the literature and does not represent a policy statement of NCI or NIH. More information about summary policies and the role of the PDQ Editorial Boards in maintaining the PDQ summaries can be found on the About This PDQ Summary and PDQ NCI's Comprehensive Cancer Database pages.

  3. Rectal Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - General Information About Rectal Cancer

    Rectal cancer is a disease in which malignant (cancer) cells form in the tissues of the rectum. The rectum is part of the body’s digestive system. The digestive system removes and processes nutrients (vitamins,minerals,carbohydrates,fats,proteins,and water) from foods and helps pass waste material out of the body. The digestive system is made up of the esophagus,stomach,and the small ...

  4. Rectal Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Stage III Rectal Cancer

    Treatment options:Preoperative chemoradiation with fluorouracil (5-FU) for patients with clinically staged T3 or T4 rectal adenocarcinoma.Total mesorectal excision (TME) with either low anterior resection (LAR) or abdominoperineal resection (APR).Postoperative chemoradiation for patients with stage II or III rectal cancer who did not receive preoperative chemoradiation.Four to six months of 5-FU-based chemotherapy postoperatively.A clinical trial.Prior to the standard use of preoperative chemoradiation for stage II and III rectal cancer, several studies established the benefits of adjuvant combined-modality therapy for surgical stage II and III disease. Intergroup protocol 86-47-51 (MAYO-864751) demonstrated a 10% improvement in overall survival (OS) with the use of continuous-infusion 5-FU (225 mg/m2 /day throughout the course of radiation therapy) compared with bolus 5-FU (500 mg/m2 /day for 3 consecutive days during the first and fifth weeks of radiation).[1][Level of evidence:

  5. Colon Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Stage Information for Colon Cancer

    Treatment decisions should be made with reference to the TNM classification [1] rather than to the older Dukes or the Modified Astler-Coller classification schema.The American Joint Committee on Cancer (AJCC) and a National Cancer Institute–sponsored panel recommended that at least 12 lymph nodes be examined in patients with colon and rectal cancer to confirm the absence of nodal involvement by tumor.[2,3,4] This recommendation takes into consideration that the number of lymph nodes examined is a reflection of the aggressiveness of lymphovascular mesenteric dissection at the time of surgical resection and the pathologic identification of nodes in the specimen. Retrospective studies demonstrated that the number of lymph nodes examined in colon and rectal surgery may be associated with patient outcome.[5,6,7,8]AJCC Stage Groupings and TNM DefinitionsThe AJCC has designated staging by TNM classification to define

  6. Colorectal Cancer Screening (PDQ®): Screening - Health Professional Information [NCI] - nci_ncicdr0000062753-nci-header

    This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http://cancer.gov or call 1-800-4-CANCER.Colorectal Cancer Screening

  7. Colorectal Cancer Screening (PDQ®): Screening - Patient Information [NCI] - What is screening?

    Screening is looking for cancer before a person has any symptoms. This can help find cancer at an early stage. When abnormal tissue or cancer is found early,it may be easier to treat. By the time symptoms appear,cancer may have begun to spread. Scientists are trying to better understand which people are more likely to get certain types of cancer. They also study the things we do and the ...

  8. Colorectal Cancer Prevention (PDQ®): Prevention - Patient Information [NCI] - General Information About Colorectal Cancer

    Colorectal cancer is a disease in which malignant (cancer) cells form in the tissues of the colon or the rectum. The colon is part of the body's digestive system. The digestive system removes and processes nutrients (vitamins, minerals, carbohydrates, fats, proteins, and water) from foods and helps pass waste material out of the body. The digestive system is made up of the mouth, throat, esophagus, stomach, and the small and large intestines. The first 6 feet of the large intestine are called the large bowel or colon. The last 6 inches are the rectum and the anal canal. The anal canal ends at the anus (the opening of the large intestine to the outside of the body). Anatomy of the lower digestive system, showing the colon and other organs.Cancer that begins in the colon is called colon cancer, and cancer that begins in the rectum is called rectal cancer. Cancer that affects either of these organs may also be called colorectal cancer.See the following PDQ summaries for more information

  9. Rectal Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - nci_ncicdr0000062726-nci-header

    This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http://cancer.gov or call 1-800-4-CANCER.Rectal Cancer Treatment

  10. Colon Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - nci_ncicdr0000062954-nci-header

    This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http://cancer.gov or call 1-800-4-CANCER.Colon Cancer Treatment

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