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Colorectal Cancer Health Center

Medical Reference Related to Colorectal Cancer

  1. Rectal Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Get More Information From NCI

    Call 1-800-4-CANCERFor more information, U.S. residents may call the National Cancer Institute's (NCI's) Cancer Information Service toll-free at 1-800-4-CANCER (1-800-422-6237) Monday through Friday from 8:00 a.m. to 8:00 p.m., Eastern Time. A trained Cancer Information Specialist is available to answer your questions.Chat online The NCI's LiveHelp® online chat service provides Internet users with the ability to chat online with an Information Specialist. The service is available from 8:00 a.m. to 11:00 p.m. Eastern time, Monday through Friday. Information Specialists can help Internet users find information on NCI Web sites and answer questions about cancer. Write to usFor more information from the NCI, please write to this address:NCI Public Inquiries Office9609 Medical Center Dr. Room 2E532 MSC 9760Bethesda, MD 20892-9760Search the NCI Web siteThe NCI Web site provides online access to information on cancer, clinical trials, and other Web sites and organizations that offer support

  2. Colon Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Stage I Colon Cancer Treatment

    Because of its localized nature, stage I colon cancer has a high cure rate.Standard Treatment Options for Stage I Colon CancerSurgeryStandard treatment options for stage I colon cancer include the following:Wide surgical resection and anastomosis.Evidence (laparoscopic techniques):The role of laparoscopic techniques [1,2,3,4] in the treatment of colon cancer was examined in a multicenter, prospective, randomized trial (NCCTG-934653, now closed) comparing laparoscopic-assisted colectomy (LAC) with open colectomy.Three-year recurrence rates and 3-year overall survival rates were similar in the two groups. (Refer to the Primary Surgical Therapy section in the Treatment Option Overview section of this summary for more information.)The quality-of-life component of this trial has been published and minimal short-term quality-of-life benefits with LAC were reported.[5][Level of evidence: 1iiC]Current Clinical TrialsCheck for U.S. clinical trials from NCI's list of cancer clinical trials

  3. Colorectal Cancer Screening (PDQ®): Screening - Patient Information [NCI] - Colorectal Cancer Screening

    Tests are used to screen for different types of cancer.Some screening tests are used because they have been shown to be helpful both in finding cancers early and decreasing the chance of dying from these cancers. Other tests are used because they have been shown to find cancer in some people; however, it has not been proven in clinical trials that use of these tests will decrease the risk of dying from cancer. Scientists study screening tests to find those with the fewest risks and most benefits. Cancer screening trials also are meant to show whether early detection (finding cancer before it causes symptoms) decreases a person's chance of dying from the disease. For some types of cancer, finding and treating the disease at an early stage may result in a better chance of recovery. Clinical trials that study cancer screening methods are taking place in many parts of the country. Information about ongoing clinical trials is available from the NCI Web site.Studies show that screening for

  4. Colorectal Cancer Prevention (PDQ®): Prevention - Health Professional Information [NCI] - Overview

    Note: Separate PDQ summaries on Colorectal Cancer Screening; Colon Cancer Treatment; and Rectal Cancer Treatment are also available.Factors Associated With Increased Risk of Colorectal CancerExcessive alcohol useBased on solid evidence from observational studies, excessive alcohol use is associated with an increased risk of colorectal cancer (CRC).[1,2,3]Magnitude of Effect: A pooled analysis of eight cohort studies estimated an adjusted relative risk (RR) of 1.41 (95% confidence interval [CI], 1.16–1.72) for consumption exceeding 45 g/day.Study Design: Cohort studies.Internal Validity: Fair.Consistency: Fair.External Validity: Fair.Cigarette smokingBased on solid evidence, cigarette smoking is associated with increased incidence and mortality from CRC.Magnitude of Effect: A pooled analysis of 106 observational studies estimated an adjusted RR (current smokers vs. never smokers) for developing CRC of 1.18 (95% CI, 1.11–1.25).Study Design:

  5. Colon Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - nci_ncicdr0000062954-nci-header

    This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http://cancer.gov or call 1-800-4-CANCER.Colon Cancer Treatment

  6. Lynch Syndrome

    Important It is possible that the main title of the report Lynch Syndromes is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. ...

  7. Colon Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Treatment Option Overview for Colon Cancer

    Table 6. Standard Treatment Options for Stages 0–III Colon CancerStage (TNM Staging Criteria)Standard Treatment OptionsStage 0 Colon CancerSurgeryStage I Colon CancerSurgeryStage II Colon CancerSurgeryStage III Colon CancerSurgery Adjuvant chemotherapyTable 7. Treatment Options for Stage IV and Recurrent Colon CancerStage (TNM Staging Criteria)Treatment OptionsTreatment of Liver MetastasisSurgeryNeoadjuvant chemotherapyLocal ablationAdjuvant chemotherapyIntra-arterial chemotherapyTreatment of Stage IV and Recurrent Colon CancerSurgeryChemotherapy and targeted therapySecond-line chemotherapyPrimary Surgical TherapyStandard treatment for patients with colon cancer has been open surgical resection of the primary and regional lymph nodes for localized disease.The role of laparoscopic techniques [1,2,3,4] in the treatment of colon cancer has been examined in two studies.Evidence (laparoscopic techniques):A multicenter, prospective, randomized, noninferiority trial

  8. Colorectal Cancer Prevention (PDQ®): Prevention - Patient Information [NCI] - Changes to This Summary (06 / 03 / 2013)

    The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.Changes were made to this summary to match those made to the health professional version.

  9. Rectal Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Treatment Option Overview

    Primary Surgical TherapyThe primary treatment for patients with rectal cancer is surgical resection of the primary tumor. Local excision of clinical T1 tumors is an acceptable surgical technique for appropriately selected patients. For all but T1 tumors, a mesorectal excision is the treatment of choice. Very selected patients with T2 tumors may be candidates for local excision. Local failure rates in the range of 4% to 8% following rectal resection with appropriate mesorectal excision (total mesorectal excision [TME] for low/middle rectal tumors and mesorectal excision at least 5 cm below the tumor for high rectal tumors) have been reported.[1,2,3,4,5]The low incidence of local relapse following meticulous mesorectal excision has led some investigators to question the routine use of adjuvant radiation therapy. Because of an increased tendency for first failure in locoregional sites only, the impact of perioperative radiation therapy is greater in rectal

  10. Colon Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - nci_ncicdr0000062687-nci-header

    This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http://cancer.gov or call 1-800-4-CANCER.Colon Cancer Treatment

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