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    Colorectal Cancer Health Center

    Medical Reference Related to Colorectal Cancer

    1. Colon Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Questions or Comments About This Summary

      If you have questions or comments about this summary, please send them to Cancer.gov through the Web site's Contact Form. We can respond only to email messages written in English.

    2. Colorectal Cancer - Description of the Evidence

      BackgroundIncidence and mortalityColorectal cancer (CRC) is the third most common malignant neoplasm worldwide [1] and the second leading cause of cancer deaths (irrespective of gender) in the United States.[2] It is estimated that there will be 142,820 new cases diagnosed in the United States in 2013 and 50,830 deaths due to this disease.[2] Between 2005 and 2009, CRC incidence rates in the United States declined by 4.1% per year among adults aged 50 years and older.[2] For the past 20 years, the mortality rate has been declining in both men and women. Between 2005 and 2009, the mortality rate declined by 2.4% per year in men and by 3.1% per year in women. In adults younger than 50 years, CRC incidence rates increased by about 1.1% per year.[2] The overall 5-year survival rate is 64%. About 5% of Americans are expected to develop the disease

    3. Colorectal Cancer, Metastatic or Recurrent - Treatment Options for Colon Cancer

      Stage 0 (Carcinoma in Situ)Treatment of stage 0 (carcinoma in situ) may include the following types of surgery:Local excision or simple polypectomy.Resection and anastomosis. This is done when the tumor is too large to remove by local excision.Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage 0 colon cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.Stage I Colon CancerTreatment of stage I colon cancer usually includes the following:Resection and anastomosis.Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage I colon cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the

    4. Colorectal Cancer, Metastatic or Recurrent - About This PDQ Summary

      About PDQPhysician Data Query (PDQ) is the National Cancer Institute's (NCI's) comprehensive cancer information database. The PDQ database contains summaries of the latest published information on cancer prevention, detection, genetics, treatment, supportive care, and complementary and alternative medicine. Most summaries come in two versions. The health professional versions have detailed information written in technical language. The patient versions are written in easy-to-understand, nontechnical language. Both versions have cancer information that is accurate and up to date and most versions are also available in Spanish.PDQ is a service of the NCI. The NCI is part of the National Institutes of Health (NIH). NIH is the federal government's center of biomedical research. The PDQ summaries are based on an independent review of the medical literature. They are not policy statements of the NCI or the NIH.Purpose of This SummaryThis PDQ cancer information summary has current

    5. Colon Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Recurrent Rectal Cancer

      Recurrent rectal cancer is cancer that has recurred (come back) after it has been treated. The cancer may come back in the rectum or in other parts of the body, such as the colon, pelvis, liver, or lungs.

    6. Colorectal Cancer, Metastatic or Recurrent - Get More Information From NCI

      Call 1-800-4-CANCERFor more information, U.S. residents may call the National Cancer Institute's (NCI's) Cancer Information Service toll-free at 1-800-4-CANCER (1-800-422-6237) Monday through Friday from 8:00 a.m. to 8:00 p.m., Eastern Time. A trained Cancer Information Specialist is available to answer your questions.Chat online The NCI's LiveHelp® online chat service provides Internet users with the ability to chat online with an Information Specialist. The service is available from 8:00 a.m. to 11:00 p.m. Eastern time, Monday through Friday. Information Specialists can help Internet users find information on NCI Web sites and answer questions about cancer. Write to usFor more information from the NCI, please write to this address:NCI Public Inquiries Office9609 Medical Center Dr. Room 2E532 MSC 9760Bethesda, MD 20892-9760Search the NCI Web siteThe NCI Web site provides online access to information on cancer, clinical trials, and other Web sites and organizations that offer support

    7. Colorectal Cancer, Metastatic or Recurrent - Changes to This Summary (02 / 27 / 2014)

      The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.Editorial changes were made to this summary.This summary is written and maintained by the PDQ Screening and Prevention Editorial Board, which is editorially independent of NCI. The summary reflects an independent review of the literature and does not represent a policy statement of NCI or NIH. More information about summary policies and the role of the PDQ Editorial Boards in maintaining the PDQ summaries can be found on the About This PDQ Summary and PDQ NCI's Comprehensive Cancer Database pages.

    8. Colon Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Questions or Comments About This Summary

      If you have questions or comments about this summary, please send them to Cancer.gov through the Web site's Contact Form. We can respond only to email messages written in English.

    9. Colorectal Cancer, Metastatic or Recurrent - Treatment Option Overview for Colon Cancer

      Table 6. Standard Treatment Options for Stages 0–III Colon CancerStage (TNM Staging Criteria)Standard Treatment OptionsStage 0 Colon CancerSurgeryStage I Colon CancerSurgeryStage II Colon CancerSurgeryStage III Colon CancerSurgery Adjuvant chemotherapyTable 7. Treatment Options for Stage IV and Recurrent Colon CancerStage (TNM Staging Criteria)Treatment OptionsTreatment of Liver MetastasisSurgeryNeoadjuvant chemotherapyLocal ablationAdjuvant chemotherapyIntra-arterial chemotherapyTreatment of Stage IV and Recurrent Colon CancerSurgeryChemotherapy and targeted therapySecond-line chemotherapyPrimary Surgical TherapyStandard treatment for patients with colon cancer has been open surgical resection of the primary and regional lymph nodes for localized disease.The role of laparoscopic techniques [1,2,3,4] in the treatment of colon cancer has been examined in two studies.Evidence (laparoscopic techniques):A multicenter, prospective, randomized, noninferiority trial

    10. Colorectal Cancer, Metastatic or Recurrent - To Learn More About Colon Cancer

      For more information from the National Cancer Institute about colon cancer, see the following:Colon and Rectal Cancer Home PageWhat You Need to Know About™ Cancer of the Colon and RectumColorectal Cancer PreventionColorectal Cancer ScreeningTests to Detect Colorectal Cancer and PolypsUnusual Cancers of ChildhoodCryosurgery in Cancer Treatment: Questions and AnswersDrugs Approved for Colon CancerTargeted Cancer TherapiesUnderstanding Cancer Series: Targeted Therapies (Advances in Targeted Therapies)Genetic Testing for Hereditary Cancer SyndromesFor general cancer information and other resources from the National Cancer Institute, see the following:What You Need to Know About™ CancerUnderstanding Cancer Series: CancerCancer StagingChemotherapy and You: Support for People With CancerRadiation Therapy and You: Support for People With CancerCoping with Cancer: Supportive and Palliative CareQuestions to Ask Your Doctor About CancerCancer LibraryInformation For

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