If you are:
Only When Necessary: NEONATAL WITHDRAWAL/RESP.DEPRESS. W/CHRONIC OR HIGH DOSE; SMALL TERATOGENIC RISK
Precaution: LOW MW, MAY BE EXCRETED; MONITOR FOR INFANT WITHDRAWAL SYMPTOMS
An adult over 60:
management or monitoring precaution: Pulmonary-DO NOT USE in opioid intolerance. Life-threatening respiratory depression more likely to occur due to altered clearance. Use cautiously with respiratory disease, when initiating, titrating and giving with other respiratory depressants. Neuro/Psych-Risk for confusion, delirium and falls. Avoid treatment with 3 or more CNS active agents. Gastrointestinal-Increased rate of constipation in the elderly. Cardiovascular-Vasodilation may predispose to orthostatic hypotension.
Giving nucynta to a child under 12:
Severe Precaution: Risk of respiratory depression. Safety and efficacy not established.