If you are:
Only When Necessary: INSUFFICIENT HUMAN DATA AVAILABLE; TERATOGENIC IN ANIMALS AT 25 TIMES THE MRHD
No Known Risk: AMOUNT EXCRETED REPORTED TO BE LOW WITH LOW INFANT ORAL BIOAVAILABILITY
Precaution: POOR ORAL BIOAVAILABILITY AND SHORT HALF-LIFE; UNLIKELY TO AFFECT INFANT.
An adult over 60:
management or monitoring precaution: General-May be more sensitive to CNS and cardiac adverse reactions. Consider dose reduction due to reduced clearance in the elderly.
management or monitoring precaution: Cardiovascular-Increased risk of cardiovascular side effects: tachycardia, Neuro/Psych-Increased risk of neuropsychological adverse events.
Giving lido-epi-with-8-4-sod-bicarb-syringe to a child under 12:
Severe Precaution: Risk of systemic toxicity. Monitor for CNS toxicity (e.g. restlessness, dizziness, drowsiness, blurred vision) with prolonged infusion, repeated injections or application. Limited safety data available.