What Medicines Can Make Your Blood Sugar Spike?

Medically Reviewed by Michael Dansinger, MD on May 21, 2023
2 min read

If you have diabetes or high blood sugar, you probably know some of the things that cause your glucose (another name for blood sugar) to go up. Like a meal with too many carbohydrates, or not enough exercise. But other medicines you might take to keep yourself healthy can cause a spike, too.

Medicines you get with a prescription and some that you buy over the counter (OTC) can be a problem for people who need to control their blood sugar.

Prescription medicines that can raise your glucose include:

OTC medicines that can raise your blood sugar include:

Even though these medicines can raise your blood sugar, it doesn’t mean that you shouldn’t take them if you need them. The most important thing is to work with your doctor on the right way to use them.

If you have diabetes or you’re watching your blood sugar, ask your doctor before you take new medicines or change any medicines, even if it’s just something for a cough or cold. (Remember, just being sick can raise your blood sugar.)

Make sure your doctor knows all the medicines you take -- for diabetes or any other reason. If one of them may affect your blood sugar, they may prescribe a lower dose or tell you to take the medicine for a shorter time. You may need to check your blood sugar more often while you’re taking the medicine, too.

Also, remember to do the things you know will help keep your levels under control. Exercise, eat right, and take any diabetes medicines that you need.