If you are:
Only When Necessary: CAUTION WITH USE; RISK OF PLATELET AGGREGATION IN NEWBORN
Only When Necessary: EVIDENCE FOR MALFORMATIONS; CAN REDUCE UTERINE BLOOD FLOW CAUSING FETAL HYPOXIA
Precaution: LIMITED AMOUNT MAY BE EXCRETED DUE TO LOW MW; MONITOR INFANT FOR RESP DEPRESS
Precaution: ORAL BIOAVAILABILITY LOW; INFANT EXPOSURE MAY BE MINIMAL
An adult over 60:
management or monitoring precaution: Neuro/Psych-Anticholinergic effects may cause sedation, worsen cognitive impairment and increase fall risk. Gastrointestinal-May cause or worsen pre-existing constipation. Genitourinary-Best avoided in patients with urinary retention from any cause.
management or monitoring precaution: Cardiovascular-Elderly are more sensitive to tachycardia and hypertensive effects. May exacerbate symptomatic coronary insufficiency. Genitourinary-May cause urinary retention. Neuro/Psych-May worsen cognitive impairment in some elderly with dementia. Insomnia risk.
Giving promethazine-vc to a child under 12:
Contraindication: Risk of CNS excitation. Do not use age <6 years without clinician consult.
Contraindication: Potential for fatal respiratory depression age < 2 years. Avoid use.
Severe Precaution: Caution:use the lowest effective dose due to risk of respiratory depression.