Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
How this interaction occurs is not known.
What might happen:
The amount of tacrolimus in your blood may decrease. This may increased the risk of your organ transplant failing.
What you should do about this interaction:
Let your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together. Your doctor may want to check the amount of tacrolimus in your blood and change the amount of tacrolimus you are taking.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
1.Cancidas (caspofungin acetate) US prescribing information. Merck & Co., Inc. January, 2013.
2.Stone J, Holland S, Wickersham P, Deutsch P, Winchell G, Hesney M, Miller R, Freeman A, Dilzer S, Lasseter K. Drug interactions between caspofungin and tacrolimus (abstract A-13). Presented at the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, Illinois. December, 2001.