This medication is used to treat and prevent wheezing and trouble breathing caused by ongoing lung disease (e.g., asthma, emphysema, chronic bronchitis). Oxtriphylline belongs to a class of drugs known as xanthines. It works in the airways by relaxing muscles, opening air passages to improve breathing, and decreasing the lungs' response to irritants. Controlling symptoms of breathing problems can decrease time lost from work or school.
This medication does not work immediately and should not be used for sudden attacks of breathing trouble. Your doctor should prescribe a quick-relief medicine/inhaler (e.g., salbutamol) for sudden attacks of shortness of breath/asthma while you are taking this medication. You should always have a quick-relief inhaler with you. Consult your doctor or pharmacist for more details.
If you have the liquid form, use a medication-measuring device to carefully measure the prescribed dose. Do not use a household spoon because you may not get the correct dose.
Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day.
Tell your doctor if your condition persists or worsens.
Stomach pain/cramping, nausea, vomiting, diarrhea, loss of appetite, headache, trouble sleeping, irritability, restlessness, nervousness, shaking, flushing, and increased urination may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
In the US -
Before using oxtriphylline, tell your doctor or pharmacist if you are allergic to it; or to theophylline, theobromine, or caffeine; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: a certain breathing disorder (cystic fibrosis), diabetes, glaucoma, heart problems (e.g., congestive heart failure, irregular heartbeat), high blood pressure, kidney disease, liver disease (e.g., cirrhosis), seizures, stomach/intestinal ulcer, thyroid disease.
This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.
Liquid forms of this product may contain sugar and/or alcohol. Caution is advised if you have diabetes, alcohol dependence, liver disease, or any other condition that requires you to limit/avoid these substances in your diet. Ask your doctor or pharmacist about using this product safely.
If you develop a fever/flu-like symptoms while taking this medication, tell your doctor promptly. The dose of your medicine may need to be adjusted.
Before having surgery, tell your doctor or dentist that you are taking this medication.
The elderly may be at greater risk for side effects while using this drug.
Caution is advised when using this drug in children because they may be more sensitive to its effects. Some manufacturers recommend that it not be used in children younger than 10 years.
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. Changes in your body during the last 3 months of pregnancy may affect the amount of this drug in your blood. Your doctor should carefully monitor the amount of drug in your blood, as well as any side effects, so that your dose may be changed if needed.
This drug passes into breast milk and may have undesirable effects on a nursing infant (e.g., irritability). Consult your doctor before breast-feeding.
Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.
Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: adenosine, adrenaline-like drugs (e.g., ephedrine, phenylephrine, pseudoephedrine), allopurinol, aminoglutethimide, antiarrhythmic drugs (e.g., mexiletine, propafenone), anti-seizure drugs (e.g., carbamazepine, phenytoin, phenobarbital), benzodiazepines (e.g., diazepam, flurazepam), beta blockers (e.g., propranolol), hormonal birth control, cimetidine, digoxin, disulfiram, fluvoxamine, interferon, macrolide antibiotics (e.g., erythromycin, clarithromycin), isoproterenol, lithium, methotrexate, moricizine, pentoxifylline, quinolones (e.g., ciprofloxacin, enoxacin), rifampin, St John's wort, sulfinpyrazone, tacrine, thiabendazole, ticlopidine, verapamil, zileuton.
Check the labels on all your medicines (e.g., cough-and-cold products, diet aids) because they may contain ingredients that could increase the side effects of this medication. Ask your pharmacist about using those products safely.
Tobacco/marijuana smoking decreases blood levels of this medication. Tell your doctor if you smoke or have recently stopped smoking. Your dose of medication may need to be adjusted.
Caffeine and alcohol can increase the side effects of this medication. Avoid drinking large amounts of beverages containing alcohol or caffeine (e.g., coffee, tea, some sodas) or eating large amounts of chocolate.
Some diets (e.g., high protein/low carbohydrate or high carbohydrate/low protein) may change the effect of oxtriphylline. Tell your doctor if you are following a diet plan or eat beef every day. The dose of your medicine may need to be adjusted.
Oxtriphylline is very similar to theophylline. Do not take medications containing theophylline while using oxtriphylline.
This medication may interfere with certain laboratory tests (e.g., blood sugar, cholesterol, uric acid, dipyridamole-thallium imaging tests), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.
Laboratory tests for drug blood levels may be affected by other drugs/foods, possibly causing false test results. Tell laboratory personnel and all your doctors if you take or use any of the following products: caffeine, theobromine, chocolate, furosemide, sulfathiazole, phenylbutazone, probenecid, acetaminophen, cefazolin, cephalothin.
This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: agitation, nausea, frequent vomiting, trouble sleeping, unusual thirst, fever, ringing in the ears, seeing flashes of light, fast/irregular heartbeat, seizures, confusion, chest pain.
Do not share this medication with others.
Laboratory and/or medical tests (e.g., theophylline blood levels) should be performed periodically to monitor your progress or check for side effects. It is important that you do not miss your medication or take extra doses for 2 to 3 days before your theophylline blood levels are checked. Consult your doctor for more details.
If you miss a dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.
MEDICAL ALERT: Your condition can cause complications in a medical emergency. For information about enrolling in MedicAlert, call 1-888-633-4298 (US) or 1-800-668-1507 (Canada).
Information last revised April 2014. Copyright(c) 2014 First Databank, Inc.
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