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progesterone micronized vaginal

Important Note

Common Brand Name(s): Crinone, Prochieve

Warnings
Uses
Side Effects
Precautions
Interactions
Overdose
progesterone micronized vaginal Uses

This medication is used to treat infertility in women who do not make enough of a certain natural hormone called progesterone. Progesterone works by preparing the lining of the womb to receive a fertilized egg. This hormone is needed to maintain pregnancy.

This medication is also used to restore menstrual cycles in women whose cycles have stopped.

How to use progesterone micronized vaginal

Read the Patient Information Leaflet provided by your pharmacist before you start using progesterone gel and each time you get a refill. If you have any questions regarding the information, consult your doctor or pharmacist.

This medication is for vaginal use only. Remove the wrapper and prepare the applicator for use as shown in the instructions. There are additional instructions for preparing the applicator if you use this medication at altitudes above 2,500 feet (762 meters).

To treat infertility, use this medication usually once or twice a day as directed by your doctor. If you become pregnant, continue to use this medication for 10-12 weeks as directed until your body is able to make its own progesterone.

If you are using this medication to restore your menstrual cycle, use it usually every other day up to a total of 6 doses, or as directed by your doctor.

If you are directed to use any other vaginal products, separate their application from progesterone gel by at least 6 hours.

Use this medication regularly in order to get the most benefit from it. Remember to use it at the same time(s) of the day. Dosage is based on your medical condition and response to therapy.

progesterone micronized vaginal Side Effects

Bloating, cramps, stomach pain, constipation, diarrhea, nausea, breast swelling/pain, pain around the vaginal area, drowsiness, tiredness, decreased interest in sex, joint pain, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

You may develop a vaginal discharge containing little white balls of gel from using this medication. This is normal and harmless. However, if you develop any unusual vaginal discharge, itching, or odor, notify your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur: mental/mood changes (e.g., depression, nervousness, mood swings), signs of water weight gain (e.g., swollen feet/ankles), increased urination at night, abnormal vaginal bleeding, breast lumps, yellowing of the eyes or skin.

Seek immediate medical attention if any of these rare but very serious side effects occur: pain/redness/swelling of arms or legs, trouble breathing, chest pain, weakness on one side of the body, slurred speech, vision changes.

A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

progesterone micronized vaginal Precautions

Before using progesterone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: unusual vaginal bleeding that has not been diagnosed by your doctor, liver disease, cancer of the breast or female reproductive organs, a miscarriage with some tissue remaining in the womb, blood clots.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: seizures, migraines, asthma, heart disease, kidney disease, depression, diabetes.

Although unlikely, this medication can cause blood clots. Your risk is increased if you will be having surgery or if you need to stay in a chair or bed for a long period of time (e.g., a long plane flight). Notify your doctor beforehand of any of these events. Special precautions may need to be taken in these circumstances while you are using this drug.

If you have diabetes, this medication may make it harder to control your blood sugar levels. Tell your doctor immediately if you develop symptoms of high blood sugar, such as unusual increased thirst and urination. Be sure to check your blood sugar levels regularly.

This drug may make you drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages. In general, alcohol is not recommended for pregnant or possibly pregnant women due to the increased risk of harm to the baby.

This medication may be used in pregnancy as directed by your doctor. Consult your doctor for more details.

This drug passes into breast milk. Consult your doctor before breast-feeding.

progesterone micronized vaginal Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug include: drugs affecting liver enzymes that remove progesterone from your body (such as rifampin, St. John's wort, azole antifungals including itraconazole, certain anti-seizure medicines including carbamazepine/phenobarbital/phenytoin).

If you are directed to use any other vaginal products, separate their application from progesterone gel by at least 6 hours.

progesterone micronized vaginal Overdose

If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. This medicine may be harmful if swallowed.

NOTES:

Do not share this medication with others.

Keep all appointments with your doctor and the laboratory. You should have a complete physical examination that includes blood pressure measurements and breast/pelvic examinations at regular intervals (e.g., once a year) or as directed by your doctor. Follow your doctor's instructions on how to examine your own breasts and report any lumps immediately. You should also be regularly screened for cervical cancer (e.g., Pap test). Consult your doctor for more details.

MISSED DOSE:

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

STORAGE:

Store at room temperature 77 degrees F (25 degrees C) away from light and moisture. Brief storage between 59-86 degrees F (15-30 degrees C) is permitted. Do not store in the bathroom. Keep all medicines away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

Information last revised November 2013. Copyright(c) 2013 First Databank, Inc.

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