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Heart Disease Health Center

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Heart Disease: Pericardial Disease (Percarditis)

Pericardial disease, or pericarditis, is inflammation of any of the layers of the pericardium. The pericardium is a thin fibrous membrane sac that surrounds the heart and consists of:

  • An inner layer (visceral pericardium) that envelopes the entire heart.
  • An outer layer (parietal pericardium) comprising the outer fibrous sac.
  • A middle fluid layer to prevent friction between the parietal pericardium and visceral pericardium.

What Causes Pericarditis?

Causes of pericarditis include:

  • Infections
  • Heart surgery
  • Heart attack
  • Trauma
  • Tumors
  • Cancer
  • Radiation
  • Autoimmune diseases (such as rheumatoid arthritis, lupus, or scleroderma)

For some people, no cause can be found.

Pericarditis can be acute (occurring suddenly) or chronic (long-standing).

What Are the Symptoms of Pericarditis?

When present, they may include:

  • Chest pain. This pain is different from angina (pain caused by coronary artery disease). It may be sharp and located in the center of the chest. The pain may radiate to the neck and shoulders, and occasionally, the arms and back. It is made worse when lying down, coughing, or swallowing and relieved by sitting forward.
  • Low-grade fever.

  • Increased heart rate.

How Is Pericarditis Diagnosed?

Your doctor can diagnose pericarditis based on:

Other tests may be performed to determine the cause of pericarditis.

How Is Pericarditis Treated?

Treatment is based on the cause and may include:

  • Nonsteroidal anti-inflammatory agents (NSAIDs) to decrease the pain and inflammation.
  • Steroids, used occasionally for severe attacks.
  • Antibiotics, if the pericarditis is due to infection.

Most patients recover in two to four weeks.

What Is Constrictive Pericarditis?

The symptoms are the same as pericarditis, with the addition of:

What Are the Symptoms of Constrictive Pericarditis?

The symptoms are the same as pericarditis, with the addition of:

How Is Constrictive Pericarditis Diagnosed?

The same tests used to diagnose pericarditis are used to diagnose constrictive pericarditis. Other diagnostic tests used for constrictive pericarditis include:

How Is Constrictive Pericarditis Treated?

Treatment may include:

  • Analgesics and anti-inflammatory agents to treat pain or inflammation.
  • Diuretics to treat heart failure symptoms.
  • Antiarrhythmics to treat any heart arrhythmias, such as atrial fibrillation
  • Pericardiectomy (the surgical removal of the stiff pericardium from the heart).

Reviewed by the doctors at The Cleveland Clinic Heart Center.

WebMD Medical Reference provided in collaboration with the Cleveland Clinic

Reviewed by David W. Stein, MD on December 01, 2006
Edited by Cynthia Dennison Haines, MD on October 01, 2005
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