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Atherosclerosis - Topic Overview

How does atherosclerosis cause an aortic aneurysm?

Atherosclerosis is one of the major causes of abdominal aortic aneurysm.

The wall of the aorta (and all blood vessels) is a dynamic tissue made up of living cells that need nutrients and oxygen. Many of these nutrients seep from the inside of the blood vessel through the walls to nourish the rest of the blood vessel. When the inner lining of the vessel is covered with an atherosclerotic plaque, nutrients can no longer seep through sufficiently. The cells receive no oxygen, and some of them die. As the atherosclerosis progresses and cells continue to die, the walls become weaker and weaker.

At some point, a critical relationship is reached between the pressure experienced in the center of the blood vessel, the wall tension, and the strength of the wall itself. When this point is reached, the wall begins to dilate (grow larger) in the area of the plaque. As the diameter of the vessel grows, the wall tension increases, leading to even more dilation. The end result is an aneurysm.

WebMD Medical Reference from Healthwise

Last Updated: February 13, 2013
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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