Skip to content

    Inflammatory Bowel Disease Health Center

    Font Size

    Crohn's Drugs That Target Your Immune System

    What Are Biologics?

    These drugs also affect your immune system. But they focus solely on the inflammation in your gut, where they target certain proteins that play a role in inflammation.

    Doctors use biologics if you have moderate to severe Crohn's that hasn’t responded well to other medications. They also use it to treat open, draining fistulas.

    Some examples of biologics are:

    Do Biologics Have Side Effects?

    Yes. But because of the way they work, they tend to cause fewer problems than other drugs used for Crohn's disease.

    Your doctor will still watch you carefully, especially for signs of infection. Although rare, lymphoma and blood disorders can happen.

    Before you take one of these drugs, let your doctor know if you have a heart condition or a disease that affects your nervous system.

    You may have side effects at the injection site, like:

    • Redness
    • Itching
    • Bruising
    • Pain
    • Swelling

    Other possible side effects include:

    WebMD Medical Reference

    Reviewed by Jennifer Robinson, MD on November 05, 2015
    1 | 2

    Today on WebMD

    woman with pains in abdomen
    Get personalized tips.
    doctor talking with female patient
    10 questions for your doctor.
    woman clutching at stomach
    Causes, symptoms, treatments, and more.
    butter curls
    What to eat and avoid.
    Living With Crohns Slideshow
    Ulcerative Colitis Surgery Slideshow
    crohns disease healthcheck
    Ulcerative Colitis Health Check
    Crohns Symptoms
    Ulcerative Colitis Diet
    Crohns Prebiotic
    woman holding stomach