Find Information About:

Drugs & Supplements

Get information and reviews on prescription drugs, over-the-counter medications, vitamins, and supplements. Search by name or medical condition.

Pill Identifier

Pill Identifier

Having trouble identifying your pills?

Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill.

Get Started

My Medicine

Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.

Get Started

WebMD Health Experts and Community

Talk to health experts and other people like you in WebMD's Communities. It's a safe forum where you can create or participate in support groups and discussions about health topics that interest you.

  • Second Opinion

    Second Opinion

    Read expert perspectives on popular health topics.

  • Community


    Connect with people like you, and get expert guidance on living a healthy life.

Got a health question? Get answers provided by leading organizations, doctors, and experts.

Get Answers

Sign up to receive WebMD's award-winning content delivered to your inbox.

Sign Up

Lupus Health Center

Font Size

Lupus (Systemic Lupus Erythematosus) - Symptoms

Lupus symptoms depend on what body organs are affected and how seriously they are affected.

Common symptoms

Many people have these symptoms:

  • Fatigue:Lupus causes mild to extreme fatigue. Even mild cases of lupus make it hard to do daily activities and exercise. Increased fatigue is a classic sign that a symptom flare is about to occur.
  • Joint and muscle pain: Joints may be painful, red, and warm. They may swell. Morning stiffness may also be felt. Lupus arthritis often occurs on both sides of the body at the same time. It's most often felt in the wrists, the small joints of the hands, and the elbows, knees, and ankles.
  • Skin problems:Skin rashes are often an important clue to the diagnosis. Many people have a butterfly rash camera.gif over the cheeks and bridge of the nose. Other common skin symptoms include skin sores or flaky red spots on the arms, hands, face, neck, or back; mouth or lip sores; and a scaly, red or purple raised rash on the face, neck, scalp, ears, arms, and chest.
  • Sensitivity to light: Exposure to ultraviolet light (such as sunlight or tanning parlors) typically makes the skin rash worse and can trigger lupus flares. Many people with lupus are sensitive to light, with fair-skinned people tending to be more sensitive.
  • Fever: People with lupus will sometimes have a low-grade fever related to the disease. Fever is sometimes a first sign of the disease.
  • Changes in weight: People with lupus may lose weight when their disease is active (flaring).
  • Swollen glands: Over time, people with lupus may get swollen lymph glands during a flare.
  • Headaches: These are usually related to stress and tension but can be related to a lupus flare. Many people who have lupus get migraine headaches.

Other symptoms

Other conditions with symptoms similar to lupus include fibromyalgia and chronic fatigue syndrome.

    WebMD Medical Reference from Healthwise

    Last Updated: September 09, 2014
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
    Next Article:

    Today on WebMD

    grocery shopping list
    And the memory problems that may come with it.
    Lupus rash on nails
    A detailed, visual guide.
    sunburst filtering through leaves
    You might be extra sensitive to UV light. Read on.
    fruit drinks
    For better focus in your life.
    Woman rubbing shoulder
    Bag of cosmetics
    young woman hiding face
    pregnant woman
    5 Lupus Risk Factors
    Young adult couple
    doctor advising patient
    sticky notes on face

    WebMD Special Sections