Skip to content

Melanoma/Skin Cancer Health Center

Medical Reference Related to Melanoma Skin Cancer

  1. Treatment Option Overview

    There are different types of treatment for patients with melanoma. Different types of treatment are available for patients with melanoma. Some treatments are standard (the currently used treatment),and some are being tested in clinical trials. Before starting treatment,patients may want to think about taking part in a clinical trial. A treatment clinical trial is a research study meant to ...

  2. Small Choroidal Melanoma

    The natural history of small choroidal melanoma remains poorly understood. Small,pigmented choroidal lesions cannot always be differentiated reliably on examination. Growth is a presumed indicator of malignant potential.[ 1 ] Although patients diagnosed with small choroidal tumors were not eligible for participation in the Collaborative Ocular Melanoma Study,these patients were offered ...

  3. General Information About Skin Cancer

    Skin cancer is a disease in which malignant (cancer) cells form in the tissues of the skin. The skin is the body’s largest organ. It protects against heat,sunlight,injury,and infection. Skin also helps control body temperature and stores water,fat,and vitamin D. The skin has several layers,but the two main layers are the epidermis (upper or outer layer) and the dermis (lower or inner ...

  4. Stage II Melanoma

    Note: Some citations in the text of this section are followed by a level of evidence. The PDQ editorial boards use a formal ranking system to help the reader judge the strength of evidence linked to the reported results of a therapeutic strategy. (Refer to the PDQ summary on Levels of Evidence for more information.) Stage II melanoma is defined by the following clinical stage groupings: T2b,...

  5. Interventions With Inadequate Evidence as to Whether They Reduce Risk of Melanoma

    Sunscreen Use and Ultraviolet (UV) Radiation Avoidance Benefits There is inadequate evidence to determine whether the avoidance of sunburns or the use of sunscreen alters the incidence of cutaneous melanoma. Magnitude of Benefit: Unknown. Study Design: Primarily cohort or case-control studies. A post-hoc analysis of one randomized controlled trial of regular sunscreen use (vs. use at the ...

  6. Get More Information From NCI

    Sources of further information about Skin Cancer Treatment.

  7. Get More Information From NCI

    National Cancer Institute for more cancer information.

  8. Stage I Melanoma

    Stage I melanoma is defined by the following clinical stage groupings: T1a,N0,M0 T1b,N0,M0 T2a,N0,M0 STANDARD TREATMENT OPTIONS: Current evidence suggests that lesions <2 mm thick may be treated conservatively with radial excision margins of 1 cm. A randomized trial compared narrow margins (1 cm) with wide margins (at least 3 cm) in patients with melanomas no thicker than 2 mm.[ 1,2 ] ...

  9. Cellular and Molecular Classification of Melanoma

    Following is a list of clinicopathologic cellular subtypes of malignant melanoma. These should be considered descriptive terms of historic interest only as they do not have independent prognostic or therapeutic significance. Superficial spreading.Nodular.Lentigo maligna.Acral lentiginous (palmar/plantar and subungual).Miscellaneous unusual types: Mucosal lentiginous (oral and genital).Desmoplastic.Verrucous.Molecular characterization of melanoma is an active area of research. Activating mutations in the BRAF (V-raf murine sarcoma viral oncogene homolog B1) gene, first reported in 2002, are the most frequent mutation in cutaneous melanoma. Approximately 40% to 60% of malignant melanomas harbor a single nucleotide transversion. The majority have a mutation that results in a substitution from valine to glutamic acid at position 600 BRAF (V600E); less frequent mutations include valine 600 to lysine or arginine residues (V600K/R).[1] Drugs that target this mutation by inhibiting BRAF are

  10. About PDQ

    PDQ IS A COMPREHENSIVE CANCER DATABASE AVAILABLE ON NCI'S WEB SITE. PDQ is the National Cancer Institute's (NCI's) comprehensive cancer information database. Most of the information contained in PDQ is available online at NCI's Web site.

Displaying 151 - 160 of 222 Articles << Prev Page 12 13 14 15 16 17 18 19 20 21 Next >>

Today on WebMD

Malignant melanoma
About 40-50 percent of those who live to be 65 may get it. Here’s how to spot early.
Woman checking out tan lines
There’s a dark side to that strive for beauty. See them here.
 
sauteed cherry tomatoes
Fight cancer one plate at a time.
Lung cancer xray
See it in pictures, plus read the facts.
 
12 Ways to Protect Your Skin from Melanoma
ARTICLE
precancerous lesions slideshow
SLIDESHOW
 
Do You Know Your Melanoma ABCs
VIDEO
15 Cancer Symptoms Men Ignore
ARTICLE
 
screening tests for men
SLIDESHOW
Vitamin D
SLIDESHOW
 
Is That Mole Skin Cancer
VIDEO
Brilliant sun rays
Quiz
 

WebMD Special Sections