Find Information About:

Drugs & Supplements

Get information and reviews on prescription drugs, over-the-counter medications, vitamins, and supplements. Search by name or medical condition.

Pill Identifier
WebMD

Pill Identifier

Having trouble identifying your pills?

Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill.

Get Started
My Medicine
WebMD

My Medicine

Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.

Get Started

WebMD Health Experts and Community

Talk to health experts and other people like you in WebMD's Communities. It's a safe forum where you can create or participate in support groups and discussions about health topics that interest you.

  • Second Opinion
    WebMD

    Second Opinion

    Read expert perspectives on popular health topics.

  • Community
    WebMD

    Community

    Connect with people like you, and get expert guidance on living a healthy life.

Got a health question? Get answers provided by leading organizations, doctors, and experts.

Get Answers

Sign up to receive WebMD's award-winning content delivered to your inbox.

Sign Up

Men's Health

Font Size
A
A
A

Prostate-Specific Antigen (PSA)

What Affects the Test

Reasons you may not be able to have the test or why the results may not be helpful include:

What To Think About

  • When combined with a digital rectal exam, the prostate-specific antigen (PSA) test may increase the chance of finding prostate cancer. To learn more, see the topic Digital Rectal Examination (DRE).
  • A PSA level within the normal ranges does not mean that prostate cancer is not present. Some men who have prostate cancer have normal PSA levels.
  • Experts disagree about the type of testing that is appropriate if the PSA level is high. The decision may depend on:
    • Results of your digital rectal exam.
    • Results of any PSA tests you have had in the past. If your PSA level gets higher in a short amount of time, follow-up testing may be recommended.
    • Your age and health.
    • The costs and risks of more tests and treatments.
  • Other prostate tests are being evaluated to determine how well they tell the difference between prostate cancer and benign prostatic hyperplasia.
    • The prostate-specific antigen density (PSAD) test compares the PSA value to the size of the prostate gland. The size of the prostate is measured using transrectal ultrasound (TRUS).
    • The PSA velocity test is a measure of how rapidly PSA levels increase over time. PSA levels increase more rapidly in men with prostate cancer and more slowly in men with prostate enlargement (benign prostatic hyperplasia).
    • A complexed prostate-specific antigen (cPSA) test may help show if a prostate biopsy should be done. This test measures the amount of several forms of PSA that are attached to proteins found in the blood.

WebMD Medical Reference from Healthwise

Last Updated: November 14, 2014
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.

Today on WebMD

man coughing
Men shouldn’t ignore.
man swinging in hammock
And how to get out it.
 
shaving tools
On your shaving skills.
muscular man flexing
Four facts that matter.
 
Food Men 10 Foods Boost Male Health
Slideshow
Thoughtful man sitting on bed
Quiz
 
Man taking blood pressure
Slideshow
doctor holding syringe
Slideshow
 
Condom Quiz
Quiz
thumbnail_angry_couple_in_bed
Slideshow
 
man running
Quiz
older couple in bed
Video