Baclofen (Lioresal) is the drug of choice for
spasticity. It is available in tablets or by delivery through a pump implanted
in the lower spinal area. Pump delivery is effective for those with severe
Dantrolene (Dantrium) is also
effective. But it may cause muscle weakness, which limits the number of
people who can use it. Other side effects may include nausea, vomiting, lack of
hunger (anorexia), and, with high dosages or prolonged use, liver
Gabapentin (Neurontin) may help relieve pain as well as
spasticity. It is usually very well tolerated and causes few side
Tysabri is approved as single therapy for the treatment of people with relapsing forms of multiple sclerosis (MS) to reduce the frequency of flare-ups and delay progression of physical disability.
After the FDA initially approved Tysabri, the drug's manufacturer took the drug off the U.S. market due to reports of a rare, but serious brain infection called PML (progressive multifocal leukoencephalopathy). But the drug returned to the market after the drugmaker included a risk-minimization program...
Severe tremors are
very hard to treat. If they do not respond to medicine, surgery may be
The U.S. Food and Drug Administration (FDA) has issued a
warning on seizure medicines and the risk of suicide and suicidal thoughts. The
FDA does not recommend that people stop using these medicines. Instead, people
who take seizure medicine should be watched closely for
warning signs of suicide. People who take seizure
medicine and who are worried about this side effect should talk to a
In this article
This information is produced and provided by the National
Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National
Institute via the Internet web site at http://
.gov or call 1-800-4-CANCER.
WebMD Medical Reference from Healthwise
March 12, 2014
This information is not intended to replace the advice of a doctor.
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