Active and Inactive Paget's Disease - Topic Overview
Paget's disease is a chronic disease that affects how
the body breaks down and rebuilds bone tissue. Paget's disease can be active or
inactive, depending on whether the bone formation process goes too quickly or
The hottest topic in medicine isn't the newest drug or the latest surgical device. It's vitamin D.
What brought the simmering debate to a boil was a 2007 study showing that people taking normal vitamin D supplements were 7% less likely to die than those who didn't take the daily supplements.
A year later, a major study found that when women with low vitamin D levels get breast cancer, they have a much higher chance of dying from their cancer than women with normal vitamin D levels.
That was surprising...
In inactive Paget's disease,
bone tissue is being broken down and rebuilt at a
normal speed. This most often occurs when you are using medicine to slow the
bone growth. The inactive state may continue even after you stop taking
medicine. This is called
Active Paget's disease
Active Paget's disease has three stages. They are:
Hot (lytic) stage. This stage occurs early in the
disease process, when bone tissue is being quickly broken down. Bones are often
more painful during this stage.
Mixed stage. This stage occurs
later in the disease process, when bone tissue is being quickly broken down and
Cold (rebuilding) stage. This stage occurs later
in the disease, when bone tissue is being quickly rebuilt.