CDC: Alarming Increase in Methadone Deaths
Deaths From Opioid Painkillers Have Tripled Since 1999
WebMD News Archive
Sept. 30, 2009 -- Methadone deaths have risen sevenfold in less than a
decade, according to a government report that largely blames the increase on
the growing use of methadone for pain relief.
Used primarily for the management of heroin addiction until the late 1990s,
methadone has become one of the most widely prescribed opioid painkillers, with
4 million prescriptions written for pain relief in 2006 alone.
It has also become one of the most deadly drugs around, the report from the
CDC’s National Center for Health Statistics (NCHS) confirms.
The report highlights the rising death rate associated with the use of
opioid painkillers such as methadone, morphine, OxyContin, Dilaudid, and
Between 1999 and 2006, according to the report:
- Deaths from the use of opioid pain relievers more than tripled in the U.S.,
from 4,000 in 1999 to 13,800 in 2006.
- 40% of all poisoning deaths in 2006 in the U.S. involved opioid
- The number of poisoning deaths involving methadone increased from 790 to
5,420 during this period.
- The opioid death rate was highest for whites, males, and people between the
ages of 35 and 54.
The Problem With Methadone
The increase in methadone deaths corresponds to the drug’s increased use for
pain relief, which began abruptly in 1999, says Nicholas Reuter, a public
health analyst who has been tracking methadone use and deaths for the Substance
Abuse and Mental Health Services Administration.
Increased concerns about the abuse potential of the pain reliever OxyContin
and the desire for a relatively inexpensive long-acting opioid painkiller led
to the shift in methadone use.
Last year, 750,000 methadone prescriptions were written for pain relief, but
only 250,000 people were treated with the drug for addiction to heroin and
other opioids, Reuter tells WebMD.
Methadone can suppress drug withdrawal symptoms as an addiction treatment
for 24 hours; the drug’s ability to suppress pain lasts just four to eight
But methadone stays in the system as long as 59 hours. Patients may feel
they need more pain relief before the drug is cleared from the body, and if
taken too often or at doses that are too high, toxic levels can build up, which
can lead to life-threatening changes in breathing and heart function.
”Many of the methadone deaths I hear about involve people who just go to
sleep at night and never wake up,” Reuter says.