Skip to content

    Pain Management Health Center

    Font Size
    A
    A
    A

    Placebo Effect May Help Treat Pain

    Pain Study Traces Placebo Effect to the Spinal Cord
    By
    WebMD Health News
    Reviewed by Louise Chang, MD

    Oct. 15, 2009 -- The "placebo effect" may help treat pain, German researchers report in Science.

    When someone experiences the placebo effect, they're responding to an inactive drug or sham procedure that isn't supposed to affect their condition.

    The placebo effect is often called psychological -- the brain believes it's getting real help and rallies, even though the placebo itself doesn't contain anything helpful.

    Now, German researchers report that when it comes to pain, the placebo effect affects activity in part of the spinal cord called the dorsal horn.

    Falk Eippert and colleagues at Germany's University Medical Center Hamburg-Eppendorf studied 15 healthy young men.

    First, the researchers applied heat to the men's arms in order to gauge their pain threshold.

    Next, they treated the men's arms with two identical, inactive creams. But the researchers told the men that one of the creams was "an extremely effective painkiller" and that the other cream was a "control cream."

    Finally, the researchers applied heat to the treated areas of the arms to stimulate the sense of pain.

    When the men's arms were treated with the fake painkiller cream before being subjected to heat, they reported less pain than when their arms were treated with the control cream. In short, they were experiencing the placebo effect, just as the researchers had planned.

    MRI scans taken during the tests showed less activity in the dorsal horn of the men's spinal cords, which is involved in sensory perception, when their arms had been treated with the fake painkiller cream.

    Exactly how that happened isn't clear. The study doesn't explain the mind-body connection between the men's beliefs about the creams and how they responded to the pain from the heat.

    But the findings may open up "new avenues" for assessing the efficacy and action of new pain treatments, Eippert and colleagues write.

    Today on WebMD

    pain in brain and nerves
    Top causes and how to find relief.
    knee exercise
    8 exercises for less knee pain.
     
    acupuncture needles in woman's back
    How it helps arthritis, migraines, and dental pain.
    chronic pain
    Get personalized tips to reduce discomfort.
     
    illustration of nerves in hand
    Slideshow
    lumbar spine
    Slideshow
     
    Woman opening window
    Slideshow
    Man holding handful of pills
    Video
     
    Woman shopping for vegetables
    Slideshow
    Sore feet with high heel shoes
    Slideshow
     
    acupuncture needles in woman's back
    Slideshow
    man with a migraine
    Slideshow