The treatment of organ-confined prostate cancer has involved cutting out, radiating, or freezing the gland to try to cure the disease. In more advanced cases, the goal has been to control the cancer for at least some time by using endocrine treatment or chemotherapy. Earlier diagnosis and improved treatment techniques in recent years have certainly led to better results. Interestingly, however, early diagnosis of prostate cancer, and/or early treatment of prostate cancer has not improved the prostate cancer specific survival or overall survival from prostate cancer.
The key to curing prostatecancer, however, ultimately will come from an understanding of the genetic basis of this disease. Genes, which are chemical compounds located on the chromosomes, determine the characteristics of individuals. Accordingly, investigators at research centers have focused on identifying and isolating the gene, or genes, responsible for prostate cancer. Studies have uncovered some of the genetic links to the disease. Now studies will be performed to try to block, or modify, the offending genes to prevent or alter the disease. Finally, vaccines to either prevent or treat prostate cancer have been developed and are in use.
His father's prostate cancer changed tennis legend John McEnroe, who turned 50 in February. McEnroe used to have at least one thing in common with ordinary guys: He rarely saw a doctor or gave his own health a lot of thought. That all changed five years ago, when his dad, now 74, was diagnosed with prostate cancer.
"It really raised my awareness level," says the four-time U.S. Open champ. He scheduled his first prostate-specific antigen test -- a screening test for prostate cancer that's also called...