Prostate Cancer, Advanced or Metastatic - Medications
Pain-relief and appetite-stimulant drugs
Pain-relief and appetite-stimulant drugs may be used when prostate cancer
has spread to other parts of the body.
- Steroids, such as hydrocortisone or prednisone,
control pain and improve appetite.
- Radioactive drugs, such as radium-223 (Xofigo), samarium-153, and strontium-89, are
called radionuclides. They are absorbed near the area of bone pain. Then the
radiation that is released helps relieve the pain caused by tumors that have
spread to the bone.
- Denosumab (Xgeva) and bisphosphonate drugs, such as pamidronate (Aredia) and zoledronic acid (Zometa), may help relieve
bone pain and prevent
osteoporosis, which is sometimes caused by long-term
Pain medicines are made that specifically treat mild,
moderate, and severe pain, as well as different types of pain such as burning
and tingling. To learn more, see:
- Cancer: Controlling Cancer Pain.
For more information, see the topic
Medicines for treating side effects
therapy can cause loss of sexual desire,
hot flashes, enlarged and painful breasts, and
- For men who have erection problems after surgery, medicines
such as sildenafil (Viagra), tadalafil (Cialis), or vardenafil (Levitra) may be
helpful. Using medicines soon after surgery may help men regain sexual function. Talk with your doctor about your situation.
- Taking a temporary break from hormone therapy can make some
side effects go away.
- To relieve breast pain, the anti-estrogen breast cancer
tamoxifen or radiation treatment is commonly used.
Tamoxifen can also help reverse breast growth. Also, it causes hot
- For hot flashes, taking a certain kind of
antidepressant may help.
Paroxetine or venlafaxine may help with hot flashes. But they have different side effects. So if you are having a problem with hot flashes, talk
with your doctor.
What to think about
Antiandrogen hormone therapy also
may cause diarrhea, breast tenderness, and nausea. Cases of liver problems,
some serious, have been reported.
Hormone therapy can also affect the bones, making them thin and brittle and more likely to break. Medicines such as bisphosphonates and denosumab may help prevent bone loss during long-term hormone therapy.