Skip to content

    HPV/Genital Warts Health Center

    Font Size
    A
    A
    A

    HPV Vaccine Exceeds Expectations

    Gardasil Gives Extra Degree of Protection Against Strains of HPV That Cause Cervical Cancer
    By
    WebMD Health News
    Reviewed by Louise Chang, MD

    Sept. 19, 2007 (Chicago) -- Researchers report that Gardasil protects against 10 additional strains of HPV that are leading causes of cervical cancer.

    Gardasil came on the market last year for preventing infection with two strains of human papillomavirus (HPV), 16 and 18, that are responsible for up to 70% of all cervical cancers, and HPV 6 and 11, which account for 90% of genital warts.

    The new study, which involved about 11,000 young women aged 15 to 26, shows that the vaccine is also 38% effective against 10 additional HPV types, which are responsible for an additional 20% of cervical cancers.

    “The new study shows that Gardasil affords an extra degree of protection for young women,” says researcher Darren R. Brown, MD, professor of medicine, microbiology and immunology at the Indiana University School of Medicine in Indianapolis.

    Gardasil Guards Against 10 More HPV Strains

    Brown’s previous research, presented at a major cancer meeting earlier this year, showed that Gardasil continues to offer nearly 100% protection against HPV types 16 and 18 five years following administration.

    The new study, presented here at a meeting of the American Society for Microbiology, shows that the vaccine also:

    • Is 38% effective against 10 additional strains of HPV that cause cervical cancer
    • Provides 45% protection against persistent infection from types 45 and 31, two other HPV strains linked to cervical cancer
    • Is 62% effective in preventing serious precancerous lesions from those two strains

    Brown says that it’s not a surprise that the vaccine offers protection against additional types of HPV, as they are all close cousins.

    “They’re related genetically, so you would expect some, but not complete, protection against additional subtypes, which is what we found," he tells WebMD.

    Today on WebMD

    HPV Vaccine Future
    Article
    STD Overview
    Slideshow
     
    STD Facts Quiz
    Quiz
    Syringes and graph illustration
    Tool
     
    Sex Drive Killers
    Slideshow
    Genital Herpes Risks Quiz
    Quiz
     
    Young couple holding hands
    Quiz
    Herpes Vaccine Study
    Video
     
    Condom Quiz
    Quiz
    HPV Symptoms Tests
    Article
     
    Get The STD Picture
    Feature
    cancer cell
    Slideshow
     

    WebMD Special Sections