ADHD Medication Chart

Short-Acting Stimulants

Side effects of these medications include some loss of appetite, weight loss, sleep problems, irritability, tics. They require frequent dosing.

The FDA has issued a warning about the risk of drug abuse with amphetamine stimulants. FDA safety advisors are also concerned about the possibility that all amphetamine and methylphenidate stimulants used for ADHD may increase the risk of heart and psychiatric problems.

Drug Name
Brand Name
Duration
4-6 hours
Dextroamphetamine
Zenzedi
3-4 hours
Dextroamphetamine and amphetamine
4-6 hours
Dexmethylphenidate
4-6 hours
Methylin,Ritalin
3-4 hours

Intermediate and Long-Acting Stimulants

Side effects of these medications include loss of appetite, weight loss, sleep problems, irritability, and tics. Long-acting medicines may have greater effects on appetite and sleep. The FDA has issued a warning about the risk of drug abuse with amphetamine stimulants. FDA safety advisors are also concerned about the possibility that all amphetamine and methylphenidate stimulants used for ADHD may increase the risk of heart and psychiatric problems.

Drug Name
Brand Name
Duration
Notes
Amphetamine sulfate Dyanavel 8-12 hours Oral solution/liquid
Amphetamine sulfate Evekeo 6 hours  
Dextroamphetamine Dexedrine Spansule 6-8 hours  
Dextroamphetamine and amphetamine Adderall XR 8-12 hours  
Dextroamphetamine and amphetamine Mydayis 12 hours  
Dexmethylophenidate
Focalin XR
6-10 hours
 
10-12 hours
 
Lisdexamfetamine
Vyvanse chewable
10-12 hours
Chewable tablet
Methylphenidate Aptensio XR 10-12 hours  
Methylphenidate Concerta 8-12 hours  
Methylphenidate Cotempla XR ODT 8-12 hours Oral disintegrating tablet/dissolvable
Methylphenidate Daytrana Transdermal patch Up to 10 hours May cause skin irritation or discoloration
Methylphenidate Metadate CD, Ritalin LA 8-10 hours  
Methylphenidate Metadate ER, Methylin ER 6-8 hours  
Methylphenidate Ritalin SR 4-8 hours  
Methylphenidate Quilichew ER

12 hours

Chewable tablet
Methylphenidate Quillivant XR 10-12 hours Oral solution/liquid

Nonstimulants

Drug Name
Brand Name
Duration
Notes
24 hours
Sleep problems, anxiety, fatigue, upset stomach, dizziness, dry mouth. Although rare, can cause liver damage. Increased risk of suicide in adults aged 18-24.
4-6 hours
Fatigue, dizziness, dry mouth, irritability, behavior problems, low blood pressure. Stopping this medicine suddenly can result in high blood pressure.
Clonidine
Catapres-TTS patch
Up to 7 days
Fatigue, dizziness, dry mouth, irritability, behavior problems, low blood pressure. Stopping this medicine suddenly can result in high blood pressure.
Clonidine
Kapvay
12 hours
Fatigue, dizziness, dry mouth, irritability, behavior problems, low blood pressure. Stopping this medicine suddenly can result in high blood pressure.
24 hours
Fatigue, dizziness, dry mouth, irritability, behavior problems, low blood pressure. Stopping this medicine suddenly can result in high blood pressure.
Guanfacine Tenex 6-8 hours Fatigue, dizziness, dry mouth, irritability, behavior problems, low blood pressure. Stopping this medicine suddenly can result in high blood pressure.

Continued

Antidepressants

Side effects include sleep problems. The FDA has also issued a warning about a connection between antidepressants and an increased risk of suicide in adults ages 18-24, especially in the first one or two months.

Drug Name
Brand Name
Duration
Notes
4-5 hours
Headaches. Although rare, may increase risk of seizures.
Bupropion
Wellbutrin SR
12 hours
Headaches. Although rare, may increase risk of seizures.
Bupropion
24 hours
Headaches. Although rare, may increase risk of seizures.
8-24 hours
Not recommended for children. Associated with rare cases of fatal heart problems.
8-24 hours
Anxiety, fatigue, upset stomach, dizziness, dry mouth, elevated heart rate, risk of heart arrhythmias.
Nortriptyline Aventyl, Pamelor 8-24 hours Anxiety, fatigue, upset stomach, dizziness, dry mouth, elevated heart rate, risk of heart arrhythmias.

ADHD Medicines and Safety

Experts generally consider these medicines safe when they are monitored properly by a professional. Serious problems are rare. Discuss the risks and benefits of these drugs with your doctor.

WebMD Medical Reference Reviewed by Smitha Bhandari, MD on June 06, 2018

Sources

SOURCES:

FDA: “FDA Directs ADHD Drug Manufacturers to Notify Patients about Cardiovascular Adverse Events and Psychiatric Adverse Events.” 

FDA: “FDA Proposes New Warnings about Suicidal Thinking, Behavior in Young Adults Who Take Antidepressant Medications.”

National Resource Center on ADHD: “Managing Medication for Adults with ADHD.” 

National Resource Center on ADHD: “Medications Used in the Treatment of ADHD.”

Pliszka, S. and the AACAP Study Group, Journal of the American Academy of Child and Adolescent Psychiatry, July 2007.

Medscape: “Once-Daily Guanfacine Approved to Treat ADHD.”

Intuniv website.

© 2018 WebMD, LLC. All rights reserved.

Pagination