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    • Depression
    • The Trial-and-Error Process of Treatment-Resistant Depression

    Therapies and Behavioral Interventions for Depression

      Next
      Video

      What Can Make Medication Less Effective?

      It’s important to find the right antidepressant at the right dose, but you should also know what interferes with them and can cause harmful interactions.

      Explore More
      Video

      What Leads to Treatment-Resistant Depression

      People with major depressive disorder are less likely to respond to the first antidepressant they are prescribed. Several things can cause that to happen.

      Article

      Addressing Substance Abuse and Ways to Help Prevent It

      Substance use can worsen your depression and make it harder to treat. Get the facts on substance use disorders and treatment-resistant depression.

      Article

      What Is Treatment-Resistant Depression?

      Patience and persistence are key with treatment-resistant depression. Learn how long to stick with a medication, and options for managing this condition.

      Article

      Who Is Most at Risk?

      Want to know why antidepressants may not work for you? Get the facts on risk factors for treatment-resistant depression.

      See More on Depression From WebMD

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