BUPROPION XL Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • agitation

If experienced, these tend to have a Less Severe expression i

  • throat irritation
  • a stuffy and runny nose
  • dry mouth
  • constipation
  • joint pain
  • dizziness
  • difficulty sleeping
  • excessive sweating
  • muscle tremors
  • decreased appetite
  • weight loss
  • headache
  • heart throbbing or pounding
  • nausea
  • diarrhea
  • nervousness
  • intense abdominal pain
  • abnormal dreams
  • anxious feelings

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • an infection
  • high blood pressure
  • abnormal heart rhythm
  • low blood pressure
  • hives

If experienced, these tend to have a Less Severe expression i

  • altered interest in having sexual intercourse
  • myoclonus, quick and involuntary muscle jerks
  • a migraine headache
  • blurred vision
  • a hearing disorder
  • bronchitis
  • stomatitis, a condition with painful swelling and sores inside the mouth
  • indigestion
  • a problem with menstrual periods
  • dry skin
  • neck pain
  • drowsiness
  • fever
  • loss of muscle coordination
  • fluid retention in the legs, feet, arms or hands
  • temporary redness of face and neck
  • increased hunger
  • nosebleed
  • cough
  • vomiting
  • difficulty swallowing
  • gas
  • an increased need to urinate often
  • generalized weakness
  • irritability
  • chest pains unrelated to heart problems
  • drug-induced hot flashes

RARE side effects

If experienced, these tend to have a Severe expression i

  • a disorder with excess antidiuretic hormone called syndrome of inappropriate antidiuretic hormone
  • a type of blood disorder with a decrease in all types of blood cells called pancytopenia
  • decreased blood platelets
  • low levels of white blood cells
  • high levels of white blood cells
  • mental problems from taking the drug
  • manic behavior
  • delusions
  • paranoia
  • suicidal behavior
  • suicidal thoughts
  • thoughts of hurting or killing others
  • a type of movement disorder called parkinsonism
  • tardive dyskinesia, a disorder characterized by involuntary movements of the face, mouth and tongue
  • increased pressure in the eye
  • disturbance in the ability of the eye to focus
  • hearing loss
  • a heart attack
  • a clot in the lung
  • complete heart block
  • atrioventricular block, a type of slow heart rhythm disorder
  • extra heartbeats
  • orthostatic hypotension, a form of low blood pressure
  • bronchospasm
  • inflammation of the esophagus
  • a stomach ulcer
  • inflammation of the large intestine
  • inflammation of the liver called hepatitis
  • bleeding of the stomach or intestines
  • erythema multiforme, a type of allergic skin reaction
  • a skin disorder with blistering and peeling skin called Stevens-Johnson syndrome
  • a condition with muscle tissue breakdown called rhabdomyolysis
  • coma
  • unconsciousness
  • hallucinations
  • seizures
  • a feeling of restlessness with inability to sit still
  • a type of abnormal movement disorder called dyskinesia
  • abnormal liver function tests
  • a significant type of allergic reaction called anaphylaxis
  • a type of allergic reaction called angioedema
  • a hypersensitivity reaction to a drug
  • secondary angle-closure glaucoma, a type of eye disorder
  • a rupture in the wall of the stomach or intestine
  • a type of bumpy skin rash called a maculopapular rash
  • pancreatitis
  • abnormal muscle movements

If experienced, these tend to have a Less Severe expression i

  • low amount of sodium in the blood
  • anemia
  • depersonalization, a disconnection of one's own sense of reality or identity
  • problems with ejaculation
  • grinding of the teeth
  • an extreme sense of wellbeing called euphoria
  • dry eye
  • bruising under the skin
  • pneumonia
  • excessive saliva production
  • the inability to have an erection
  • enlarged breasts
  • inflammation or infection of the vagina
  • bleeding not related to menstrual period
  • increased sensitivity of the skin to the sun
  • skin rash with sloughing
  • hair loss
  • hirsutism, a condition of hair growth on parts of the body normally without hair
  • muscle weakness
  • muscle stiffness
  • leg cramps
  • delirium
  • sensation of spinning or whirling
  • taste impairment
  • puffy face from water retention
  • aphasia, a loss of the ability to speak and understand language
  • a type of speech disorder called dysarthria
  • trouble breathing
  • difficult or painful urination
  • an inability to completely empty the bladder
  • involuntary leakage of urine
  • excess urination
  • urination during the night
  • a condition where there is excess sugar in the urine
  • abnormal results on an electroencephalogram, a test recording the brain's activity
  • a feeling of pins and needles on skin
  • inflammation of a vein
  • a feeling of general discomfort called malaise
  • an increased interest in having sexual intercourse
  • pain with sexual intercourse
  • fast heartbeat

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.