What should I Know Regarding Pregnancy, Nursing and Administering Irinotecan HCL Vial to Children or the Elderly?

If you are PREGNANT

  • Known or Theoretical Risk:

If you are NURSING


If you are an adult over 60

  • management or monitoring precaution: General-The starting dose of Irinotecan in patients 70 years and older for the every-3-week-dosage schedule should be 300 mg/m2. The incidence of severe diarrhea and neutropenia is higher in the elderly.

Giving Irinotecan HCL Vial to a child under 12

  • Severe Precaution: Risk of dehydration, hypokalemia, hyponatremia. Efficacy not demonstrated in pediatric trials.

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.