FOSPHENYTOIN SODIUM Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • a toxic effect on the central nervous system, which consists of the brain and spinal cord
  • nystagmus, a condition with involuntary eye movements

If experienced, these tend to have a Less Severe expression i

  • drowsiness
  • dizziness
  • nausea

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • low amount of potassium in the blood
  • confusion
  • extrapyramidal disease, a type of movement disorder
  • fluid accumulation in the brain
  • high blood pressure
  • pneumonia
  • swelling of the tongue
  • slurred speech
  • abnormal liver function tests
  • reactions at the site of the injection
  • high pressure within the skull

If experienced, these tend to have a Less Severe expression i

  • agitation
  • lazy eye
  • double vision
  • ringing in the ears
  • bruising under the skin
  • dry mouth
  • constipation
  • backache
  • muscle weakness
  • stupor
  • sensation of spinning or whirling
  • chills
  • muscle tremors
  • taste impairment
  • numbness
  • puffy face from water retention
  • headache
  • a type of speech disorder called dysarthria
  • vomiting
  • pelvic pain
  • weak reflexes
  • nervousness
  • generalized weakness
  • fast heartbeat

RARE side effects

If experienced, these tend to have a Severe expression i

  • low amount of phosphate in the blood
  • a disorder of the body's use of calcium
  • a type of blood disorder with a decrease in all types of blood cells called pancytopenia
  • anemia
  • decreased blood platelets
  • very low levels of granulocytes, a type of white blood cell
  • low levels of white blood cells
  • low levels of granulocytes, a type of white blood cell
  • increased eosinophils in the blood
  • toxicity to the nerve that controls hearing
  • hearing loss
  • a clot in the lung
  • a type of slowed heart rhythm disorder called heart block
  • slow heartbeat
  • ventricular arrhythmias, a type of abnormal heart rhythm
  • inflammation of the middle tissue heart muscle
  • significantly low blood pressure
  • acute liver failure
  • inflammation of the liver called hepatitis
  • kidney inflammation
  • kidney failure
  • a skin disorder with blistering and peeling skin called toxic epidermal necrolysis
  • a skin disorder with blistering and peeling skin called Stevens-Johnson syndrome
  • muscle inflammation
  • a type of abnormal movement disorder called dyskinesia
  • swollen lymph nodes
  • high blood sugar
  • a significant type of allergic reaction called anaphylaxis
  • a type of allergic reaction called angioedema
  • a hypersensitivity reaction to a drug
  • a yellowing of the eyes or skin from buildup of bilirubin called jaundice
  • multiple organ failure
  • purple glove syndrome, a skin condition where the extremities become swollen, purple and painful
  • a type of skin disorder called acute generalized exanthematous pustulosis
  • a type of significant allergic skin reaction called DRESS syndrome

If experienced, these tend to have a Less Severe expression i

  • a yeast infection of the vagina and vulva
  • porphyria
  • visual sensitivity to light
  • dilated pupils
  • indigestion
  • inflammation or infection of the vagina
  • skin discoloration
  • difficulty sleeping
  • muscle twitching
  • a distorted sense of smell called parosmia
  • visible water retention
  • small reddish-purplish pin-point sized spots on skin
  • diarrhea
  • difficult or painful urination
  • an inability to completely empty the bladder
  • involuntary leakage of urine
  • excess urination
  • decreased urine production
  • exaggerated deep reflexes
  • weakness and wasting of the body
  • accumulation of fluid or edema in the male genitals
Drug Survey

Are you currently using fosphenytoin injection?

This survey is being conducted by the WebMD marketing sciences department.

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.