Midodrine HCL

COMMON BRAND(S): ProAmatine

GENERIC NAME(S): Midodrine

OTHER NAME(S): Midodrine Tablet

WARNINGS:

Midodrine should only be used in carefully selected patients. When you are lying on your back, this medication causes a significant increase in blood pressure. Your blood pressure will be monitored carefully during treatment.

Who should not take Midodrine HCL?

Show More
Uses

Uses

This medication is used for certain patients who have symptoms of low blood pressure when standing. This condition is also known as orthostatic hypotension. Midodrine is used in people whose daily activities are severely affected by this condition, even after other treatments are used (e.g., support stockings). It is known as a sympathomimetic (alpha receptor agonist) that acts on the blood vessels to raise blood pressure.

How to use Midodrine HCL

Take this medication by mouth with or without food as directed by your doctor, usually 3 times daily (at least 3 to 4 hours between doses). Follow all your doctor's instructions carefully. This drug is taken during daytime hours, when people stand most often. This medicine should not be taken after the evening meal or less than 4 hours before bedtime. Taking your dose is not recommended if you plan to lie down for a long time afterward (for example, if you plan on taking a nap).

Dosage is based on your medical condition and response to treatment. Usually, your doctor will start you at a low dose and gradually increase your dose in order to reduce side effects. Do not increase your dose or take it more frequently than prescribed.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day.

Tell your doctor if your condition persists or worsens. This drug should be continued only in those people whose symptoms improve during treatment.

Side Effects

Side Effects

Skin tingling, chills, "goose bumps," stomach pain, or urinary problems (strong/frequent urge to urinate, frequent urination, trouble urinating) may occur. Less common side effects include dry mouth, dizziness, drowsiness, trouble sleeping, or leg cramps. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

This medication can cause your blood pressure to increase, especially when you are lying down (supine hypertension). Stop taking midodrine and contact your doctor right away if you experience the following signs of supine hypertension: pounding heartbeat, pounding in the ears, headache, blurred vision.

Tell your doctor right away if you have any serious side effects, including: slow heartbeat, unusual feeling in the chest, fainting, pressure/fullness in the head, confusion, anxiety, weakness, vision problems.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Precautions

Before taking midodrine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this drug, tell your doctor your entire medical history, including: high blood pressure, pheochromocytoma, overactive thyroid (hyperthyroidism), difficulty urinating (due to urinary retention or an enlarged prostate), heart disease, liver disease, kidney disease, diabetes.

Get up slowly to reduce dizziness when rising from a sitting or lying position.

This drug may rarely make you dizzy or drowsy or blur your vision. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).

Before having surgery, tell your doctor or dentist that you are taking this medication.

This medication is not recommended for use during pregnancy. It may harm an unborn baby. If you become pregnant or think you may be pregnant, tell your doctor right away. Consult your doctor for more details.

It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.

Interactions

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products have ingredients that could raise your blood pressure. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen).

Overdose

Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include "goose bumps," difficulty urinating, feeling cold.

Notes

Do not share this medication with others.

Blood pressure checks (lying, sitting, and standing) should be routinely taken. Share the results with your doctor. (See also Side Effects section.)

You may lessen high blood pressure while lying down by sleeping with the head of the bed lifted up.

Laboratory and/or medical tests (e.g., kidney function, liver function) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.Information last revised October 2019. Copyright(c) 2019 First Databank, Inc.

Images
midodrine 5 mg tablet
midodrine 5 mg tableticonicon
midodrine 5 mg tablet

color
light orange
shape
round
imprint
G 422
midodrine 10 mg tablet
midodrine 10 mg tableticonicon
midodrine 10 mg tablet

color
light green
shape
round
imprint
G 423
midodrine 2.5 mg tablet
midodrine 2.5 mg tableticonicon
midodrine 2.5 mg tablet

color
white
shape
round
imprint
G 421
midodrine 10 mg tablet
midodrine 10 mg tableticonicon
midodrine 10 mg tablet

color
blue
shape
round
imprint
E 149
midodrine 5 mg tablet
midodrine 5 mg tableticonicon
midodrine 5 mg tablet

color
white
shape
round
imprint
M, MH 2
midodrine 10 mg tablet
midodrine 10 mg tableticonicon
midodrine 10 mg tablet

color
white
shape
round
imprint
M, MH 3
midodrine 2.5 mg tablet
midodrine 2.5 mg tableticonicon
midodrine 2.5 mg tablet

color
white
shape
round
imprint
M, MH 1
midodrine 5 mg tablet
midodrine 5 mg tableticonicon
midodrine 5 mg tablet

color
reddish-orange
shape
round
imprint
logo and 43
midodrine 2.5 mg tablet
midodrine 2.5 mg tableticonicon
midodrine 2.5 mg tablet

color
white
shape
round
imprint
logo and 40
midodrine 5 mg tablet
midodrine 5 mg tableticonicon
midodrine 5 mg tablet

color
pink
shape
round
imprint
US 5, 212
midodrine 10 mg tablet
midodrine 10 mg tableticonicon
midodrine 10 mg tablet

color
purple
shape
round
imprint
US 10, 213
midodrine 2.5 mg tablet
midodrine 2.5 mg tableticonicon
midodrine 2.5 mg tablet

color
white
shape
round
imprint
US 2.5, 211
midodrine 5 mg tablet
midodrine 5 mg tableticonicon
midodrine 5 mg tablet

color
orange
shape
round
imprint
APO, MID 5
midodrine 2.5 mg tablet
midodrine 2.5 mg tableticonicon
midodrine 2.5 mg tablet

color
white
shape
round
imprint
APO, MID 2.5
midodrine 10 mg tablet
midodrine 10 mg tableticonicon
midodrine 10 mg tablet

color
light blue
shape
round
imprint
APO, MID 10
midodrine 2.5 mg tablet
midodrine 2.5 mg tableticonicon
midodrine 2.5 mg tablet

color
white
shape
round
imprint
logo and 40
midodrine 2.5 mg tablet
midodrine 2.5 mg tableticonicon
midodrine 2.5 mg tablet

color
white
shape
round
imprint
APO, MID 2.5
midodrine 5 mg tablet
midodrine 5 mg tableticonicon
midodrine 5 mg tablet

color
orange
shape
round
imprint
APO, MID 5
midodrine 5 mg tablet
midodrine 5 mg tableticonicon
midodrine 5 mg tablet

color
reddish-orange
shape
round
imprint
logo and 43
midodrine 10 mg tablet
midodrine 10 mg tableticonicon
midodrine 10 mg tablet

color
white
shape
round
imprint
P, 874
midodrine 5 mg tablet
midodrine 5 mg tableticonicon
midodrine 5 mg tablet

color
white
shape
round
imprint
P, 849
midodrine 2.5 mg tablet
midodrine 2.5 mg tableticonicon
midodrine 2.5 mg tablet

color
white
shape
round
imprint
P, 814
midodrine 5 mg tablet
midodrine 5 mg tablet

color
light orange
shape
round
imprint
G 422
This medicine is a light orange, round, scored, tablet imprinted with "G 422".
midodrine 10 mg tablet
midodrine 10 mg tablet

color
light green
shape
round
imprint
G 423
This medicine is a light green, round, scored, tablet imprinted with "G 423".
midodrine 2.5 mg tablet
midodrine 2.5 mg tablet

color
white
shape
round
imprint
G 421
This medicine is a white, round, scored, tablet imprinted with "G 421".
midodrine 10 mg tablet
midodrine 10 mg tablet

color
blue
shape
round
imprint
E 149
This medicine is a blue, round, tablet imprinted with "E 149".
midodrine 5 mg tablet
midodrine 5 mg tablet

color
white
shape
round
imprint
M, MH 2
This medicine is a white, round, scored, tablet imprinted with "M" and "MH 2".
midodrine 10 mg tablet
midodrine 10 mg tablet

color
white
shape
round
imprint
M, MH 3
This medicine is a white, round, scored, tablet imprinted with "M" and "MH 3".
midodrine 2.5 mg tablet
midodrine 2.5 mg tablet

color
white
shape
round
imprint
M, MH 1
This medicine is a white, round, scored, tablet imprinted with "M" and "MH 1".
midodrine 5 mg tablet
midodrine 5 mg tablet

color
reddish-orange
shape
round
imprint
logo and 43
This medicine is a reddish-orange, round, scored, tablet imprinted with "logo and 43".
midodrine 2.5 mg tablet
midodrine 2.5 mg tablet

color
white
shape
round
imprint
logo and 40
This medicine is a white, round, scored, tablet imprinted with "logo and 40".
midodrine 5 mg tablet
midodrine 5 mg tablet

color
pink
shape
round
imprint
US 5, 212
This medicine is a pink, round, scored, tablet imprinted with "US 5" and "212".
midodrine 10 mg tablet
midodrine 10 mg tablet

color
purple
shape
round
imprint
US 10, 213
This medicine is a purple, round, scored, tablet imprinted with "US 10" and "213".
midodrine 2.5 mg tablet
midodrine 2.5 mg tablet

color
white
shape
round
imprint
US 2.5, 211
This medicine is a white, round, scored, tablet imprinted with "US 2.5" and "211".
midodrine 5 mg tablet
midodrine 5 mg tablet

color
orange
shape
round
imprint
APO, MID 5
This medicine is a orange, round, scored, tablet imprinted with "APO" and "MID 5".
midodrine 2.5 mg tablet
midodrine 2.5 mg tablet

color
white
shape
round
imprint
APO, MID 2.5
This medicine is a white, round, scored, tablet imprinted with "APO" and "MID 2.5".
midodrine 10 mg tablet
midodrine 10 mg tablet

color
light blue
shape
round
imprint
APO, MID 10
This medicine is a light blue, round, scored, tablet imprinted with "APO" and "MID 10".
midodrine 2.5 mg tablet
midodrine 2.5 mg tablet

color
white
shape
round
imprint
logo and 40
This medicine is a white, round, scored, tablet imprinted with "logo and 40".
midodrine 2.5 mg tablet
midodrine 2.5 mg tablet

color
white
shape
round
imprint
APO, MID 2.5
This medicine is a white, round, scored, tablet imprinted with "APO" and "MID 2.5".
midodrine 5 mg tablet
midodrine 5 mg tablet

color
orange
shape
round
imprint
APO, MID 5
This medicine is a orange, round, scored, tablet imprinted with "APO" and "MID 5".
midodrine 5 mg tablet
midodrine 5 mg tablet

color
reddish-orange
shape
round
imprint
logo and 43
This medicine is a reddish-orange, round, scored, tablet imprinted with "logo and 43".
midodrine 10 mg tablet
midodrine 10 mg tablet

color
white
shape
round
imprint
P, 874
This medicine is a white, round, scored, tablet imprinted with "P" and "874".
midodrine 5 mg tablet
midodrine 5 mg tablet

color
white
shape
round
imprint
P, 849
This medicine is a white, round, scored, tablet imprinted with "P" and "849".
midodrine 2.5 mg tablet
midodrine 2.5 mg tablet

color
white
shape
round
imprint
P, 814
This medicine is a white, round, scored, tablet imprinted with "P" and "814".

Drug Survey

Are you taking Midodrine HCL?

Are you considering switching to Midodrine HCL?

How satisfied are you with the results?

VERY POOR
POOR
FAIR
GOOD
EXCELLENT

Are you planning to see a doctor about switching your medication?

How long have you been taking Midodrine HCL?

Are you planning to see a doctor about switching your medication?

This survey is being conducted by the WebMD marketing sciences department.Read More

Thanks for taking our survey!

Recommended For You

Find a doctor near you

Free Rx Coupon

Save up to 80% on your prescriptions.

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.