What should I Know Regarding Pregnancy, Nursing and Administering to Children or the Elderly?

If you are pregnant

  • Not Recommended:
  • Not Recommended:
  • If you are nursing

  • Precaution: LIMITED AMOUNT MAY BE EXCRETED DUE TO LOW MW; MONITOR INFANT FOR RESP DEPRESS
  • Precaution: MONITOR FOR SIGNS OF RESPIRATORY DEPRESSION AND INCREASED DROWSINESS
  • If you are an adult over 60

  • management or monitoring precaution: Neuro/Psych-Anticholinergic effects may cause sedation, worsen cognitive impairment and increase fall risk. Gastrointestinal-May cause or worsen pre-existing constipation. Genitourinary-Best avoided in patients with urinary retention from any cause.
  • management or monitoring precaution: Renal-Adjust dose for renal impairment due to renally cleared metabolite. Neuro/Psych-Risk for delirium, increased confusion, falls and seizures with accumulation. Avoid treatment with 3 or more CNS active agents. General-Consider naloxone order.
  • Pediatric use

  • Severe Precaution: Increased sensitivity to effects, adverse CNS effects and respiratory depression due to decreased elimination in neonates. With any opioid, access to naloxone for emergency reversal can mitigate risk from accidental ingestion/overdose.
  • Severe Precaution: Risk of adverse CNS effects and respiratory depression. With any opioid, access to naloxone for emergency reversal can mitigate risk from accidental ingestion/overdose.
  • Severe Precaution: Potential for fatal respiratory depression age < 2 years. Avoid use.
  • Severe Precaution: Caution:use the lowest effective dose due to risk of respiratory depression.
  • Drug Survey

    Are you currently using Mepergan injection?

    This survey is being conducted by the WebMD marketing sciences department.

    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.